This is an unofficial archive of PsychonautWiki as of 2025-08-11T15:14:44Z. Content on this page may be outdated, incomplete, or inaccurate. Please refer to the original page for the most up-to-date information.
Anxiety suppression
Anxiety suppression can be described as the partial to complete suppression of a person’s ability to feel anxiety, nervousness, general unease and negative feelings of psychological tension. The experience of this effect may decrease anxiety-related behaviour such as rumination, muscular tension, panic attacks, and restlessness.
Psychoactive substances
Compounds within our psychoactive substance index which may cause this effect include:
- 1,4-Butanediol
- 2-FA
- 2M2B
- 3-Cl-PCP
- 3-FA
- 3-FEA
- 3-FMA
- 3-HO-PCE
- 3-HO-PCP
- 3-MMC
- 3-MeO-PCE
- 3-MeO-PCMo
- 3-MeO-PCP
- 4-AcO-DiPT
- 4-FA
- 4-MeO-PCP
- 5-Hydroxytryptophan
- 6-APB
- 6-APDB
- Acetylfentanyl
- Alcohol
- Alprazolam
- Amanita muscaria
- Aniracetam
- Armodafinil
- Baclofen
- Barbiturates
- Benzodiazepines
- Bromantane
- Bromazepam
- Buprenorphine
- Cannabidiol
- Cannabis
- Carisoprodol
- Clonazepam
- Clonazolam
- Clonidine
- Codeine
- Coluracetam
- Creatine
- Cyclazodone
- Deschloroetizolam
- Deschloroketamine
- Desomorphine
- Desoxypipradrol
- Dextromethorphan
- Dextropropoxyphene
- Diazepam
- Diclazepam
- Dihydrocodeine
Experience reports
Anecdotal reports which describe this effect within our experience index include:
- Experience: 36mg 4-AcO-DiPT - Truly, one for the psychedelic animals among us
- Experience: 660ug LSD - First bad trip
- Experience:100 mg- Actually Lifechanging
- Experience:120µg LSD - First Bad Acid Trip, Psychosis
- Experience:150mg MDMA + 20mg 2C-B - I designed it this way myself
- Experience:20mg (insufflated) - permanent all-encompassing states of unity and interconnectedness
- Experience:20mg Etizolam - Smoking Etizolam
- Experience:225mg Pregabalin +Cannabis -Bliss and Serenity; a hedonistic evening
- Experience:25mg 2C-B - Hard raving at home
- Experience:25mg Quetiapine - Nice buzz
- Experience:260 mg Ketamine (insufflated) - Lost in Paisley
- Experience:2C-P (approx. 35mg) - Asymmetrical Terror and the Geometric Sea
- Experience:2mg 25C-NBOMe - Experimental trip to test personal limits of NBOMes
- Experience:2mg Etizolam - Here be dragons
- Experience:3 bowls of cannabis indica - I wrote down unintelligible gibberish
- Experience:3-MMC: Weak substitute? No way!
- Experience:3.5g psilocybe cubensis - Relinquishing of Material Chains/Fear and Desolation
- Experience:300mg DXM + 25mg DMT + Cannabis - A crazy night
- Experience:300ug LSD - Profound religious experience
- Experience:300µg LSD - Togetherness and the Silent Dusk
- Experience:3mg Etizolam - A Comedown Drug
- Experience:40mg Zolpidem / 20mg Diazepam - Please Don't Do This
- Experience:60mg 4-AcO-DMT Nonstop Quasi-Orgasmic Objectless Euphoria
- Experience:60mg Zolpidem - A Delirious Adventure
- Experience:70mg Lisdexamfetamine (oral) - My first stimulant experience
- Experience:7500mg - Analysis of gabapentin
- Experience:800 seeds LSA - My First Trip Ever
- Experience:An experiement combining mangoes and cannabis
- Experience:BK-2C-B - Various experiences
- Experience:DXM and Cannabis: 100mg - Unexpected Strong Trip
- Experience:Datura and nicotine smoked - 4 and ~15 hits; was actually quite pleasant
- Experience:Diazepam (20/10mg, Oral) - Comfortably Drunk
- Experience:Kratom + Phenibut + Cannabis - Warm Bliss
- Experience:MXE: 37.5 mg - Calm and Cloudy Bliss
- Experience:Mushrooms (~0.5 g) - Autonomous Voice
- Experience:Nightmare flipping
- Experience:Psilocybin Mushroom (0.16 g, Oral) - Dosage Independent Intensity
- Experience:Zopiclone hppd?
- Experience:~150mg MDA(oral) - a case of mistaken identity