Talk:Olanzapine
initial draft. This will contain a myriad of information and will be formatted later :) --Corticosteroid (talk) 22:58, 20 October 2017 (CEST)
Olanzapine, first branded as Zyprexa, is a widely-used antipsychotic substance of the thienobenzodiazepine chemical class. It produces sedating and neuroleptic effects when administered. Olanzapine is known to cause weight gain and help induce Diabetes mellitus type 2 more frequently than other antipsychotics. On the other hand, it has less of a chance of producing tardive dyskinesia or an extrapyramidal reaction and also seems to treat schizophrenia very effectively.[1] Olanzapine can be given by mouth and can also be injected into a muscle. Telenzepine is another agent that shares the thienobenzodiazepine core structure.
- (doses:
- Light: 2.5 mg
- Medium: 5 to 7.5 mg
- Heavy: 10 mg
- Strong: 10 mg +)
Subjective effects
Physical effects
- Hunger - This often happens over a course of treatment and not with one use.
- Sedation
- Salivation
Cognitive effects
- Anxiety suppression - This is mediated by olanzapine's antidopaminergic, antiadrenergic, and serotonergic action rather than GABA-related activity.
- ↑ Leucht, S., Cipriani, A., Spineli, L., Mavridis, D., Örey, D., Richter, F., ... & Kissling, W. (2013). Comparative efficacy and tolerability of 15 antipsychotic drugs in schizophrenia: a multiple-treatments meta-analysis. The Lancet, 382(9896), 951-962.