This is an unofficial archive of PsychonautWiki as of 2025-08-08T03:33:20Z. Content on this page may be outdated, incomplete, or inaccurate. Please refer to the original page for the most up-to-date information.
Talk:Ecgetrin
This article is in the 'Talk' namespace because it is an unfinished draft. This section is used to host drafts for unpublished articles as well as discussions for published ones. If you'd like to use this area to discuss this draft, please do so in the 'Discussion' section at the very bottom of the page. This notice will be removed once this draft has been approved for publication by an administrator.
It may contain incorrect information, particularly with respect to dosage, duration, subjective effects, toxicity and other risks. It may also not meet PW style and grammar standards.
Ecgetrin (also known as Ecgedetrine) is a research chemical and synthetic tropane alkaloid stimulant that is from a similar class to that of Scopolamine, Hyoscyamine or Cocaine but lacks one of the ester/ether/oxygen moieties. It is of the substituted tropanes class. Ecgetrin is predicted to be a dopamine reuptake inhibitor and is structurally related to Troparil and while it has stimulating effects on the CNS, Ecgetrin, as a Troparil or desoxyphenyl type tropane compound (2,5-diethoxy phenyl-methyl tropane-2-acetyllethane) is reported to not effect the sympathetic nervous system in the same way benzoyl tropanes historically have been. It in general is a more balanced reuptake inhibitor, potentially with affinity as an agonist ligand of serotonin and dopamine because of the ethoxy ether moities in its internal structure, as well as the less acidic nature of the ethylcarboxyl moiety at the tropane 2-position, more common in agonists versus reuptake inhibitors. Also, because the serotonin-dopamine activity is more at balance with Ecgetrin than other tropane stimulants and it does not have a high reactivity with most ions it is generally, of non-esterified aromatic tropanes thus less likely to cause adverse or specific physical body loads or abnormal physical sensations or experiences.
Disclaimer: The effects listed below cite the Subjective Effect Index (SEI), an open research literature based on anecdotal user reports and the personal analyses of PsychonautWikicontributors. As a result, they should be viewed with a healthy degree of skepticism.
It is also worth noting that these effects will not necessarily occur in a predictable or reliable manner, although higher doses are more liable to induce the full spectrum of effects. Likewise, adverse effects become increasingly likely with higher doses and may include addiction, severe injury, or death ☠.
{{effects/base
|
Physical effects
If applicable, a brief paragraph summary of the substance's physical effects may be included here.
You may select physical effects to add below here.
If applicable, a brief paragraph summary of the substance's cognitive effects may be included here.
You may select from a list of cognitive effects to add below here.
This toxicity and harm potential section is a stub.
As a result, it may contain incomplete or even dangerously wrong information! You can help by expanding upon or correcting it. Note: Always conduct independent research and use harm reduction practices if using this substance.
It is strongly recommended that one use harm reduction practices when using this substance. Since it has cocaine-like effects, it would be wise to assume that it has similar toxicity. Start at low dosages (5-10mg) and work your way up from there.
Warning:Many psychoactive substances that are reasonably safe to use on their own can suddenly become dangerous and even life-threatening when combined with certain other substances. The following list provides some known dangerous interactions (although it is not guaranteed to include all of them).
Always conduct independent research (e.g. Google, DuckDuckGo, PubMed) to ensure that a combination of two or more substances is safe to consume. Some of the listed interactions have been sourced from TripSit.