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Can be considered extremely toxic when compared to other substances such as <a href="/wiki/Methamphetamine" title="Methamphetamine">Methamphetamine</a> or <a href="/wiki/MDMA" title="MDMA">MDMA</a>, Ingestion of PMA has been associated with severe tachycardia (abnormally high heart rate), <a href="/wiki/Seizure" title="Seizure">seizures</a>, <a href="/wiki/Dehydration" title="Dehydration">dehydration</a>, <a href="/wiki/Increased_bodily_temperature" title="Increased bodily temperature">hyperthermia</a>, and death