This is an unofficial archive of PsychonautWiki as of 2025-08-11T15:14:44Z. Content on this page may be outdated, incomplete, or inaccurate. Please refer to the original page for the most up-to-date information.
Talk:Dangerous drug combinations/Archive 1
Negative effects
Severe
- Serotonin Syndrome
- Psychosis
- Delusions
- Thought loops
- Panic Attacks
- Seizures
- Loss of Consciousness(Coma)
- Major Respiratory depression
- Heart Attack/Stroke
- Death
Minor
- Anxiety
- Depression
- Mood Swings
- Paranoia
- Confusion
- Amnesia
- Sedation
- Loss of motor control
- Dizziness
- Dehydration
- Nausea
- Head aches
- Vasoconstriction
- Abnormal heart beat
- minor respiratory depression
- Loss of temperature regulation
- Thought deceleration
- Suppression of emotion
- Suppression of information processing
- Suppression of language
other to include:
Prescription Drugs
MAOIs
| Dangerous combinations | ||
|---|---|---|
| MAOI interaction chart | ||
| Common MAOIs | Dangerous Interactions | Safe Interactions |
| Phenelzine | Phenethylamines | DMT (smoked) |
| Tranylcypramine | Dissociatives | DMT (oral) |
| Selegiline | Ibogaine | Mushrooms |
| cathinones | 4-AcO-DMT | |
| RIMAs | 5-htp | LSD |
| Brofaromine | Tramadol | |
| Minaprine | 4-FA / 5-IAI | |
| Pirlindole | SSRI/SNRI | |
| harmaline | TCAs | |
| Serotonin Releasers | ||
SSRI/SNRI antidepressants
None of these substances should be taken while on an SSRI, use of a prescription must be discontinued for 3-5 days before taking these substances
- 2C-T-7
- aMT / aET
- MAOI / RIMA
- DXM, MXE, PCP
- Ibogaine
- Tramadol
- 5-HTP
Anticonvulsants
- tryptamines
- phenethylamines
- Ibogaine
5-HTP
5-HTP should not be taken while under the influence of any of these drugs, it can be used before or after though
- 2C-T-7
- aMT / aET
- MAOI / RIMA
- SSRI/SNRI
- serotonin releasers