This is an unofficial archive of PsychonautWiki as of 2025-08-11T15:14:44Z. Content on this page may be outdated, incomplete, or inaccurate. Please refer to the original page for the most up-to-date information.
Orgasm depression
Template:Proofread Orgasm suppression can be described as a difficulty or complete inability to achieve orgasm. This commonly occurs as a result of tactile suppression on opioids and dissocitves which decreases ones ability to feel sexual pleasure. It can also be a result of the effect known as difficulty urinating on stimulants which seems to decrease the strength of ones kegal muscles and therefore prevent both ejaculation and orgasm within males.
Psychoactive substances
Compounds within our psychoactive substance index which may cause this effect include:
- 3-Cl-PCP
- 3-HO-PCP
- 3-MMC
- 4-FA
- 4-FMA
- 4F-EPH
- Acetylfentanyl
- Baclofen
- Buprenorphine
- Codeine
- Deschloroketamine
- Desomorphine
- Dextromethorphan
- Dextropropoxyphene
- Dihydrocodeine
- Diphenidine
- Ephenidine
- Ethylmorphine
- Fentanyl
- GHB
- HXE
- Heroin
- Hydrocodone
- Hydromorphone
- Ketamine
- Kratom
- LSA
- MDMA
- MXiPr
- Memantine
- Methadone
- Methoxetamine
- Methoxphenidine
- Morphine
- O-Desmethyltramadol
- O-PCE
- Oxycodone
- Oxymorphone
- Pethidine
- Phenibut
- Pregabalin
- Prochlorperazine
- Quetiapine
- Selective serotonin reuptake inhibitor
- Tapentadol
- Tramadol