PsychonautWiki Archive

2C-B-FLY

Revision as of 05:37, 6 May 2016 by >Oskykins (Text replacement - "{{Main|Research chemicals#Toxicity and harm potential}}" to "{| |- | 17px''Main articles: Research chemicals § Toxicity and harm potential'' ''&'' ''Responsible use § Hallucinogens'' |}")

2C-B-FLY is a psychedelic phenethylamine of the 2C-x family which was first synthesized by Aaron P. Monte. It produces psychedelic effects which typically last 6–8 hours, or up to 12 hours in larger doses.

2C-B-FLY
Chemical Nomenclature
Common names 2C-B-FLY
Substitutive name 8-bromo-2,3,6,7-benzo-dihydro-difuran-ethylamine
Systematic name [[systematic name::2-(4-bromo-2,3,6,7-tetrahydrofuro[2,3-f][1]benzofuran-8-yl)ethanamine]]
Class Membership
Psychoactive class Psychedelic
Chemical class Phenethylamine / Benzodihydrodifuran
Routes of Administration

WARNING: Always start with lower doses due to differences between individual body weight, tolerance, metabolism, and personal sensitivity. See responsible use section.



⇣ Oral
Dosage
Threshold 2 mg
Light 5 - 10 mg
Common 10 - 18 mg
Strong 18 - 25 mg
Heavy 25 mg +
Duration
Total 7 - 12 hours
Onset 30 - 60 minutes
Come up 1 - 2 hours
Peak 3 - 5 hours
Offset 2 - 3 hours
After effects 6 - 24 hours









DISCLAIMER: PW's dosage information is gathered from users and resources for educational purposes only. It is not a recommendation and should be verified with other sources for accuracy.

Interactions
Summary sheet: 2C-B-FLY

Very little is known about this substance, but it gained popularity around 2005 before becoming significantly less common after two deaths occurred in October 2009 after the ingestion of a substance that was mislabelled and sold as 2C-B-FLY but was actually Bromo-DragonFLY.[1]

It has recently become easily accessible again through online research chemical vendors where it is being sold as a designer drug.

Chemistry

 
General formula of the phenethylamine molecule

2C-B-FLY is a substituted molecule of the phenethylamine class. 2C-B-FLY features a phenyl ring bound to an amino (NH2) group through an ethyl chain and contains a bromine attached to carbon R4 of the phenyl ring. 2C-B-FLY is an atypical psychedelic phenethylamine which is closely analogous to 2C-B; 2C-B-FLY is the dihydrodifuran analog to 2C-B. 2C-B-FLY incorporates the methoxy groups bound to R2 and R5 of 2C-B into five member dihydrofuran rings fused to the central benzene ring.

2C-B-FLY belongs to a group of phenethylamine derivatives referred to as the FLY compounds, named for their insect-like appearance of two “wing-like” furan or dihydrofuran rings fused on the opposite sides of the central benzene ring.

Pharmacology

Main article: Serotonergic psychedelic

2C-B-FLY's psychedelic effects are believed to come from its efficacy at the 5-HT2A receptor as a partial agonist. It also has a high binding affinity for the 5-HT1D, 5-HT1E, 5-HT1A, 5-HT2B and 5-HT2C receptors.[2]

However, the role of these interactions and how they result in the psychedelic experience continues to remain elusive.

Subjective effects

 
 This subjective effects section is a stub.

As such, it is still in progress and may contain incomplete or wrong information.

You can help by expanding or correcting it.

The effects listed below are based upon the subjective effects index and personal experiences of PsychonautWiki contributors. The listed effects will rarely (if ever) occur all at once, but heavier dosages will increase the chances and are more likely to induce a full range of effects.

In comparison to 2C-B, this compound presents a significantly more pronounced body high, stronger visual effects and more complex geometry. For certain people, comparatively greater stomach discomfort including mild diarrhoea, gas and nausea is also present.

Physical effects

Cognitive effects

Visual effects

Enhancements

Distortions

Geometry

Hallucinatory states

Auditory effects

Toxicity and harm potential

 Main articles: Research chemicals § Toxicity and harm potential & Responsible use § Hallucinogens

The toxicity and long-term health effects of recreational 2C-B-FLY do not seem to have been studied in any scientific context and the exact toxic dose is unknown. This is because 2C-B-FLY is a research chemical with very little history of human usage. Anecdotal evidence from people within the psychonaut community who have tried 2C-B-FLY suggests that there are no negative health effects attributed to simply trying the drug by itself at low to moderate doses and using it very sparingly (but nothing can be completely guaranteed). Independent research should always be done to ensure that a combination of two or more substances is safe before consumption.

It is strongly recommended that one use harm reduction practices when using this drug.

Tolerance and addiction potential

2C-B-FLY is not habit-forming and the desire to use it can actually decrease with use. It is most often self-regulating.

Tolerance to the effects of 2C-B-FLY are built almost immediately after ingestion. After that, it takes about 3 days for the tolerance to be reduced to half and 7 days to be back at baseline (in the absence of further consumption). 2C-B-FLY presents cross-tolerance with [[Cross-tolerance::all psychedelics]], meaning that after the consumption of 2C-B-FLY all psychedelics will have a reduced effect.

 

This legality section is a stub.

As such, it may contain incomplete or wrong information. You can help by expanding it.

  • United States - 2C-B-FLY is unscheduled and uncontrolled in the United States. However, it may fall under the scope of the Federal Analog Act if it is intended for human consumption given its similarity to 2C-B.
  • United Kingdom - 2C-B-FLY is currently legal within the United Kingdom and easily accessible through the use of clearnet research chemical vendors.

See also

References

  1. ↑ Information on Reported Deaths Related to 2C-B-Fly | https://www.erowid.org/chemicals/2cb_fly/2cb_fly_death1.shtml
  2. ↑ Psychedelics and the human receptorome. | https://www.ncbi.nlm.nih.gov/pubmed/20126400
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