Diarrhea
Template:Proofread Diarrhea or diarrhoea (from the Ancient Greek word διάρροια from διά dia "through" and ῥέω rheo "flow") is the condition of having at least three loose or liquid bowel movements each day. It often lasts for a few days and can result in dehydration due to fluid loss. Signs of dehydration often begin with loss of the normal stretchiness of the skin and changes in personality. This can progress to decreased urination, loss of skin color, a fast heart rate, and a decrease in responsiveness as it becomes more severe.

In the context of psychoactive substance usage, certain compounds such as modafanil have been known induce diarreah or can at least increase the likelihood of it occurring. This is not as dangerous as the same condition when it occurs through infection as it only remains whilst one is under the influence of the compound.
Psychoactive substances
Compounds within our psychoactive substance index which may cause this effect include: