2C-x

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2C-x is the general name for the family of synthetic phenethylamines originally studied by Alexander Shulgin. Shulgin first synthesized most of the 2C-x chemicals in the 1970s and later published his findings in his book PiHKAL. The 2C-x chemicals vary in effect from being totally inactive to fully psychedelic.

The general structure for a 2C-x compound

List of 2C-x compunds

Compound	R4	Structure
2C-B	Br
2C-C	Cl
2C-D	CH3
2C-E	CH2CH3
2C-H	H
2C-I	I
2C-iP	CH(CH3)2
2C-P	CH2CH2CH3
2C-TFM	CF3
2C-T	SCH3
2C-T-2	SCH2CH3
2C-T-4	SCH(CH3)2
2C-T-7	SCH2CH2CH3
2C-T-21	SCH2CH2

Health effects, potential addiction and tolerance

The 2C-x chemicals, as with many other serotonergic psychedelics, should not be taken in combination with SSRIs (selective serotonin reuptake Inhibitor) or tricyclic antidepressants in general to avoid Serotonin Syndrome, a potentially life-threatening condition in which an abundance of serotonin is built up the body, causing many physical and cognitive health problems.

Legal status

• Austria: The 2C-x family is illegal to possess, produce and sell under the SMG (Suchtmittelgesetz Österreich) or the NPSG (Neue-Psychoaktive-Substanzen-Gesetz Österreich).
• USA: In the US, most of the 2C-x chemicals are Schedule I under the American Food and Drug Administration Safety and Innovation Act of 2012 and the Federal Analogue Act.
• Australia: Australia has a blanket ban over all substituted phenethylamines including the entire 2C-X family.
• Switzerland: Most 2C-x drugs are illegal to possess, produce and sell.
• Canada: All 2C-x phenethylamines are schedule III in Canada.
• United Kingdom: Most of the 2C-x chemical class are Class A drugs in the United Kingdom as a result of the phenethylamine catch-all clause.
• Germany: Most 2C-x compounds are controlled under BtMG Anlage I, making them illegal to manufacture, import, possess, sell, or transfer them without a license. Other 2C-x compounds are controlled by the NpSG, as they are derivatives of 2-Phenethylamine. Production, and sale is illegal. Possession and import, although illegal, is not penalized if intended for self-consumption.

See also

• Responsible use
• DOx
• 25x-NBOMe
• Psychedelics
• Phenethylamines

External links

• 2C (Wikipedia)

Literature

• Dean, B. V., Stellpflug, S. J., Burnett, A. M., & Engebretsen, K. M. (2013). 2C or not 2C: Phenethylamine Designer Drug Review. Journal of Medical Toxicology, 9(2), 172-178. https://doi.org/10.1007/s13181-013-0295-x