Template:SubstanceBox/SAM-e

Chemical Nomenclature

Common names

S-Adenosyl methionine, SAM-e, Methylguanidoacetic acid

Systematic name

(2S)-2-Amino-4-(((2S,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl)methyl-methylsulfonio)butanoate

Class Membership

Psychoactive class

Nootropic

Chemical class

Nitrogenous organic acid

Routes of Administration

WARNING: Always start with lower doses due to differences between individual body weight, tolerance, metabolism, and personal sensitivity. See responsible use section.

⇣ Oral
Dosage
Bioavailability	2-10%
Threshold	200 - 400 mg
Light	400 - 800 mg
Common	800 - 1200 mg
Strong	1200 - 1600 mg
Heavy	1600 mg +
Duration
Total	8 - 12 hours
Onset	100 - 180 minutes

DISCLAIMER: PW's dosage information is gathered from users and resources for educational purposes only. It is not a recommendation and should be verified with other sources for accuracy.