This is an unofficial archive of PsychonautWiki as of 2025-08-11T15:14:44Z. Content on this page may be outdated, incomplete, or inaccurate. Please refer to the original page for the most up-to-date information.
Temperature regulation suppression
Temperature regulation suppression can be defined as an inability to maintain a normal temperature. This results in feelings of constantly fluctuating between being uncomfortably cold[1] and uncomfortably hot. It varies in its intensity between different substances but is particularly common within stimulating compounds.
Psychoactive substances
Compounds within our psychoactive substance index which may cause this effect include:
- 1P-ETH-LAD
- 1cP-AL-LAD
- 1cP-MiPLA
- 2,5-DMA
- 2-FA
- 25B-NBOH
- 25C-NBOH
- 25C-NBOMe
- 25D-NBOMe
- 25E-NBOH
- 25I-NBOH
- 25I-NBOMe
- 2C-B-FLY
- 2C-D
- 2C-E
- 2C-H
- 2C-I
- 2C-P
- 2C-T-2
- 2C-T-21
- 2C-T-7
- 3-FEA
- 3-MMC
- 3C-E
- 3C-P
- 4-AcO-DMT
- 4-AcO-DiPT
- 4-FA
- 4-HO-DET
- 4-HO-MET
- 4-HO-MiPT
- 5-MeO-DALT
- 5-MeO-DMT
- 5-MeO-DiBF
- 6-APB
- AL-LAD
- Alcohol
- Bromo-DragonFLY
- Bufotenin
- Butylone
- DMT
- DOB
- DOC
- DOM
- Dextromethorphan
- Diphenhydramine
- ETH-LAD
- Ephylone
- Ethylone
- F-Phenibut
Experience reports
Anecdotal reports which describe this effect within our experience index include:
- Experience: 36mg 4-AcO-DiPT - Truly, one for the psychedelic animals among us
- Experience: 450 Datura seeds - Talking to Ghosts
- Experience: 5-EAPB (60mg) + 2-FMA (20mg) + 4-AcO-DMT (10mg) - Emotional catharsis
- Experience: 6mg:DOC - Carpet shop hell
- Experience:1000 Morning Glory seeds - Rediscovering the Self
- Experience:12 mg AMT - Nicely Surprised
- Experience:1g Methiopropamine - Chasing the Chalky Dragon
- Experience:1mg 25c-NBOMe - Experiment in my room
- Experience:250 seeds - Harsh body load
- Experience:2mg 25C-NBOMe - Experimental trip to test personal limits of NBOMes
- Experience:30mg - Horrible bodyload
- Experience:3g - I found god inside of myself
- Experience:4-HO-DET (20 mg, oral) - Tripping for my birthday
- Experience:4-HO-MET 22mg oral
- Experience:50mg - How's the short-term memory?
- Experience:800-900mg Ephenidine + unknown quantity flubroalzolam - Multiday Insanity
- Experience:BK-2C-B - Various experiences
- Experience:LSA (20 HWBR seeds) – A pleasant adventure with a harsh body load
- Experience:LSD (230 ug) - An amazing adventure by vikilikepsych
- Experience:Mushrooms (~0.5 g) - Autonomous Voice
- Experience:N,N-Dimethylcathinone:102 mg - A Decent, Functional Stimulant
- Experience:Unknown Dose DOC (Insufflated) - Overdosing and Terifying Ego Death
- Experience:Unknown dosage / 3 tabs - Ego death and a total break through in the snow
- Experience:~150mg MDA(oral) - a case of mistaken identity
See also
External links
References
- ↑ Walsh, S. L., Strain, E. C., Abreu, M. E., & Bigelow, G. E. (2001). Enadoline, a selective kappa opioid agonist: comparison with butorphanol and hydromorphone in humans. Psychopharmacology, 157(2), 151-162. https://doi.org/10.1007/s002130100788