2C-T-2: Difference between revisions

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'''2,5-Dimethoxy-4-ethylthiophenethylamine''' (also known as '''2C-T-2''', and '''Rosy''') is a [[Psychoactive class::psychedelic]] [[Chemical class::phenethylamine]] of the [[2C-x]] family. It was first synthesized and tested for activity in humans by [[Alexander Shulgin]] and his research group in 1981.<ref>Shulgin, Alexander. "Pharmacology Lab Notes #4". Lafayette, CA. (1981-1982). p474 (Erowid.org) | https://erowid.org/library/books_online/shulgin_labbooks/shulgin_pharmacology_notebook4_searchable.pdf</ref> Shulgin described the synthesis and activity of 2C-T-2 in his 1991 book [[PiHKAL]] ("Phenethylamines I Have Known and Loved").<ref>https://erowid.org/library/books_online/pihkal/pihkal.shtml | [[PiHKAL]] </ref>
'''2,5-Dimethoxy-4-ethylthiophenethylamine''' (also known as '''2C-T-2''', and '''Rosy''') is a [[Psychoactive class::psychedelic]] substance of the [[chemical class::phenethylamine]] chemical class that produces psychedelic effects when [[Route of administration|administered]].
It is a member of the [[2C-x family]] of psychedelic phenethylamines, all of which were derived from the systematic modification of the [[mescaline]] molecule.  


This particular substance is part of the so-called "magical half-dozen" which refers to Shulgin's self-rated most important phenethylamine compounds, all of which, with the exception of [[mescaline]] he developed and synthesized himself. They can be found within the first book of PiHKAL, and are as follows: [[Mescaline]], [[DOM]], [[2C-B]], [[2C-E]], [[2C-T-2]] and [[2C-T-7]].<ref>https://erowid.org/library/books_online/pihkal/pihkal.shtml | [[PiHKAL]] </ref>
2C-T-2 was first synthesized and tested for activity in humans by [[Alexander Shulgin]] in 1981<ref>Shulgin, Alexander. "Pharmacology Lab Notes #4". Lafayette, CA. (1981-1982). p474 (Erowid.org) | https://erowid.org/library/books_online/shulgin_labbooks/shulgin_pharmacology_notebook4_searchable.pdf</ref> and described in his 1991 book [[PiHKAL]] ("Phenethylamines I Have Known and Loved").<ref name="pihkal2CT2">Shulgin, A., & Shulgin, A. (1991).
[http://isomerdesign.com/PiHKAL/read.php?id=33 IsomerDesign: "PiHKAL" - #33 - 2C-I]. Retrieved Jan 22, 2018.</ref> It is a member of the so-called "magical half-dozen" which refers to Shulgin's self-rated most important [[phenethylamine]]-derived compounds, all of which except [[mescaline]] he developed and synthesized himself. They are found within the first book of [[PiHKAL]], and are as follows: [[Mescaline]], [[DOM]], [[2C-B]], 2C-E, [[2C-T-2]] and [[2C-T-7]].<ref name="pihkalweb">Shulgin, A., & Shulgin, A. (1991). [https://www.erowid.org/library/books_online/pihkal/pihkal.shtml Erowid Online Books: "PIHKAL" - The Chemical Story]. Retrieved April 14, 2017.</ref>


Anecdotal reports tend to characterize 2C-T-2 as a highly dose sensitive psychedelic known for its strong visuals, lucid headspace and unpredictably intense [[body load]].  
Following the initial positive results found by Shulgin's research group, a more formal study was carried out by psychedelic psychotherapy pioneer Myron J. Stolaroff who was interested in evaluating the potential use of 2C-T-2 in psychotherapy.<ref>Stolaroff, MJ; Wells, C. Preliminary results with new psychoactive agents 2C-T-2 and 2C-T-7. In Jahrbuch für Ethnomedizin und Bewußtseinsforschung (Yearbook of Ethnomedicine and the Study of Consciousness); Rätsch, C; Baker, J, Eds., 1993; Vol. 2, pp 99–117. (MAPS.org) | http://www.maps.org/images/pdf/1993_stolaroff_1.pdf</ref> Based on the experiences of forty participants in the study who took 2C-T-2, Stolaroff compared the effects favorably to [[MDMA]], describing it as more emotionally opening and permitting a wider exploration of feelings and thoughts.


Following the initial positive results found by Shulgin's research group, a more formal study was carried out by psychedelic psychotherapy pioneer by Myron J. Stolaroff who was interested in evaluating the potential use of 2C-T-2 in psychotherapy.<ref>Stolaroff, MJ; Wells, C. Preliminary results with new psychoactive agents 2C-T-2 and 2C-T-7. In Jahrbuch für Ethnomedizin und Bewußtseinsforschung (Yearbook of Ethnomedicine and the Study of Consciousness); Rätsch, C; Baker, J, Eds., 1993; Vol. 2, pp 99–117. (MAPS.org) | http://www.maps.org/images/pdf/1993_stolaroff_1.pdf</ref> Based on the experiences of forty participants in the study who took 2C-T-2, Stolaroff compared the effects favorably to [[MDMA]], describing it as more emotionally opening and permitting a wider exploration of feelings and thoughts. Although presenting a very positive evaluation of the drug, Stolaroff also noted that because it permitted repressed feelings to surface more readily than MDMA, the experience could be uncomfortable for some users.  
Anecdotal reports generally characterize 2C-T-2 as a highly dose sensitive psychedelic known for its open headspace and unpredictable [[body load]].  


Very little data exists about the pharmacological properties, metabolism, and toxicity of 2C-T-2, and it has little history of human usage. Many reports also indicate that the physical effects are too severe for those who are not already experienced with [[psychedelics]] or suffer from pre-existing physical conditions as it is known to cause powerful [[nausea]] and general bodily discomfort that may dominate the rest of the experience. It is highly advised to approach this potent, physically unpredictable, and long-lived [[psychedelic]] substance with the proper amount of precaution and [[harm reduction practices]] if choosing to use it.
Very little data exists about the pharmacological properties, metabolism, and toxicity of 2C-T-2, and it has little history of human usage. Many reports also indicate that its physical effects may be too severe for those who are not already experienced with [[psychedelics]] or suffer from pre-existing physical conditions. It is highly advised to approach this [[hallucinogenic]] substance with the proper amount of precaution and [[harm reduction practices]] if choosing to use it.


==History and culture==
==History and culture==
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