5-MeO-DiBF: Difference between revisions

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==Pharmacology==

5-MeO-DiBF likely acts as a [[Serotonin#The_5-HT_system|5-HT2A]] [[Agonist#Agonists|partial agonist]]. The [[psychedelic]] effects are believed to come from its efficacy at the 5-HT1A and 5-HT2 family of serotonin receptors. However, the role of these interactions and how they result in the psychedelic experience ~~continues~~ to remain elusive.

5-MeO-DiBF likely acts as a [[Serotonin#The_5-HT_system|5-HT2A]] [[Agonist#Agonists|partial agonist]]. The [[psychedelic]] effects are believed to come from its efficacy at the 5-HT1A and 5-HT2 family of serotonin receptors. However, the role of these interactions and how they result in the psychedelic experience continue to remain elusive.

This compound is several times less potent as a serotonin agonist than 5-MeO-DiPT. It has relatively more activity at 5-HT1A, but still shows strongest effects at the 5-HT2 family of receptors.<ref>Benzofuran bioisosteres of hallucinogenic tryptamines (PubMed.gov / NCBI) | https://www.ncbi.nlm.nih.gov/pubmed/1534585</ref><ref>Differential interactions of indolealkylamines with 5-hydroxytryptamine receptor subtypes (PubMed.gov / NCBI) | https://www.ncbi.nlm.nih.gov/pubmed/2139186</ref>

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 ==Pharmacology==
 {{Further|Serotonergic psychedelic}}
--MeO-DiBF likely acts as a [[Serotonin#The_5-HT_system|5-HT<sub>2A</sub>]] [[Agonist#Agonists|partial agonist]]. The [[psychedelic]] effects are believed to come from its efficacy at the 5-HT<sub>1A</sub> and 5-HT2 family of serotonin receptors. However, the role of these interactions and how they result in the psychedelic experience continues to remain elusive.
+-MeO-DiBF likely acts as a [[Serotonin#The_5-HT_system|5-HT<sub>2A</sub>]] [[Agonist#Agonists|partial agonist]]. The [[psychedelic]] effects are believed to come from its efficacy at the 5-HT<sub>1A</sub> and 5-HT2 family of serotonin receptors. However, the role of these interactions and how they result in the psychedelic experience continue to remain elusive.
 This compound is several times less potent as a serotonin agonist than 5-MeO-DiPT. It has relatively more activity at 5-HT1A, but still shows strongest effects at the 5-HT2 family of receptors.<ref>Benzofuran bioisosteres of hallucinogenic tryptamines (PubMed.gov / NCBI) | https://www.ncbi.nlm.nih.gov/pubmed/1534585</ref><ref>Differential interactions of indolealkylamines with 5-hydroxytryptamine receptor subtypes (PubMed.gov / NCBI) | https://www.ncbi.nlm.nih.gov/pubmed/2139186</ref>