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Talk:Extrapyramidal symptoms: Difference between revisions
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Extrapyramidal symptoms are most commonly caused by typical antipsychotic drugs that [[Antagonist|antagonize]] [[dopamine]] D2 [[receptors]]. | Extrapyramidal symptoms are most commonly caused by typical antipsychotic drugs that [[Antagonist|antagonize]] [[dopamine]] D2 [[receptors]]. | ||
The most common typical [[antipsychotics]] associated with EPS are [[haloperidol]] and fluphenazine.<ref>Note, I. (2009). Extrapyramidal adverse effects Extrapyramidal adverse effects. Biomed Res Int., 2014, 30–32. https://doi.org/10.1155/2014/656370</ref> | The most common typical [[antipsychotics]] associated with EPS are [[haloperidol]] and fluphenazine.<ref>Note, I. (2009). Extrapyramidal adverse effects Extrapyramidal adverse effects. Biomed Res Int., 2014, 30–32. https://doi.org/10.1155/2014/656370</ref> | ||
Other anti-dopaminergic drugs, like the [[Nausea suppression|antiemetic]] metoclopramide, can also result in extrapyramidal side effects.<ref>Moos, D. D., & Hansen, D. J. (2008). Metoclopramide and Extrapyramidal Symptoms: A Case Report. Journal of Perianesthesia Nursing, 23(5), 292–299. https://doi.org/10.1016/j.jopan.2008.07.006</ref> | Other anti-dopaminergic drugs, like the [[Nausea suppression|antiemetic]] metoclopramide, can also result in extrapyramidal side effects.<ref>Moos, D. D., & Hansen, D. J. (2008). Metoclopramide and Extrapyramidal Symptoms: A Case Report. Journal of Perianesthesia Nursing, 23(5), 292–299. https://doi.org/10.1016/j.jopan.2008.07.006</ref> | ||
Short and long-term use of antidepressants such as selective serotonin reuptake inhibitors ([[SSRI]]), serotonin-norepinephrine reuptake inhibitors (SNRI), and norepinephrine-dopamine reuptake inhibitors (NDRI) have also resulted in extrapyramidal symptoms. Specifically, duloxetine, sertraline, escitalopram, fluoxetine, and bupropion have been linked to the induction of extrapyramidal symptoms.<ref>Madhusoodanan, S., Alexeenko, L., Sanders, R., & Brenner, R. (2010). Extrapyramidal symptoms associated with antidepressants--a review of the literature and an analysis of spontaneous reports. Annals of Clinical Psychiatry : Official Journal of the American Academy of Clinical Psychiatrists, 22(3), 148–56. Retrieved from http://www.ncbi.nlm.nih.gov/pubmed/20680187</ref> | Short and long-term use of antidepressants such as selective serotonin reuptake inhibitors ([[SSRI]]), serotonin-norepinephrine reuptake inhibitors (SNRI), and norepinephrine-dopamine reuptake inhibitors (NDRI) have also resulted in extrapyramidal symptoms. Specifically, duloxetine, sertraline, escitalopram, fluoxetine, and bupropion have been linked to the induction of extrapyramidal symptoms.<ref>Madhusoodanan, S., Alexeenko, L., Sanders, R., & Brenner, R. (2010). Extrapyramidal symptoms associated with antidepressants--a review of the literature and an analysis of spontaneous reports. Annals of Clinical Psychiatry : Official Journal of the American Academy of Clinical Psychiatrists, 22(3), 148–56. Retrieved from http://www.ncbi.nlm.nih.gov/pubmed/20680187</ref> | ||