Isopropylphenidate: Difference between revisions

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Isopropylphenidate is a synthetic molecule of the substituted [[phenethylamine]] and [[piperidine]] classes. It contains a phenethylamine core featuring a phenyl ring bound to an amino (NH2) group via an ethyl chain. It is structurally similar to [[amphetamine]], featuring a substitution at Rα which is then incorporated into a piperidine ring ending at the terminal amine of the phenethylamine chain. Additionally, it contains an isopropyl acetate bound to R2 of its molecular structure, a noticeable departure from [[methylphenidate]], which contains a methyl group in this position.

Isopropylphenidate structurally diverges from [[ethylphenidate]] and [[methylphenidate]] by the length of the carbon chain on their acetate group. ''Iso-'' regards the side chain of one carbon atom branching into two bound methyl groups, ''phen-'' indicates the phenyl ring, ''id-'' is contracted from the piperidine ring, and ''-ate'' indicates the acetate group ~~that contains the oxygen atoms~~. Isopropylphenidate is a chiral compound, and has ~~only~~ been documented as being produced as a racemic mixture.~~{{citation needed}}~~

Isopropylphenidate structurally diverges from [[ethylphenidate]] and [[methylphenidate]] by the length of the carbon chain on their acetate group. ''Iso-'' regards the side chain of one carbon atom branching into two bound methyl groups, ''phen-'' indicates the phenyl ring, ''id-'' is contracted from the piperidine ring, and ''-ate'' indicates the acetate group. Isopropylphenidate is a chiral compound, and has been documented as being produced as a racemic mixture and exclusively as either of its enantiomers.<ref name="IPPHSynthesis">Lachman, L., & Malspeis, L. (1962). U.S. Patent No. 3060089. Washington, DC: U.S. Patent and Trademark Office. Therapeutic lower alkyl esters of alpha-phenyl-alpha-piperidyl-(2)-acetic acid</ref>

==Pharmacology==

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 Isopropylphenidate is a synthetic molecule of the substituted [[phenethylamine]] and [[piperidine]] classes. It contains a phenethylamine core featuring a phenyl ring bound to an amino (NH<sub>2</sub>) group via an ethyl chain. It is structurally similar to [[amphetamine]], featuring a substitution at R<sub>α</sub> which is then incorporated into a piperidine ring ending at the terminal amine of the phenethylamine chain. Additionally, it contains an isopropyl acetate bound to R<sub>2</sub> of its molecular structure, a noticeable departure from [[methylphenidate]], which contains a methyl group in this position.
-Isopropylphenidate structurally diverges from [[ethylphenidate]] and [[methylphenidate]] by the length of the carbon chain on their acetate group. ''Iso-'' regards the side chain of one carbon atom branching into two bound methyl groups, ''phen-'' indicates the phenyl ring, ''id-'' is contracted from the piperidine ring, and ''-ate'' indicates the acetate group that contains the oxygen atoms. Isopropylphenidate is a chiral compound, and has only been documented as being produced as a racemic mixture.{{citation needed}}
+Isopropylphenidate structurally diverges from [[ethylphenidate]] and [[methylphenidate]] by the length of the carbon chain on their acetate group. ''Iso-'' regards the side chain of one carbon atom branching into two bound methyl groups, ''phen-'' indicates the phenyl ring, ''id-'' is contracted from the piperidine ring, and ''-ate'' indicates the acetate group. Isopropylphenidate is a chiral compound, and has been documented as being produced as a racemic mixture and exclusively as either of its enantiomers.<ref name="IPPHSynthesis">Lachman, L., & Malspeis, L. (1962). U.S. Patent No. 3060089. Washington, DC: U.S. Patent and Trademark Office. Therapeutic lower alkyl esters of alpha-phenyl-alpha-piperidyl-(2)-acetic acid</ref>
 ==Pharmacology==