NEP: Difference between revisions

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'''N-Ethyl-(nor)-pentedrone''' (also known as '''N-Ethylpentedrone''', '''Ethyl-pentedrone''' or more commonly, '''NEP''') is a novel synthetic [[psychoactive class::stimulant]] substance of the [[psychoactive class::cathinone]] chemical class that produces [[cathinone]]-like [[stimulating]], [[disinhibition|disinhibiting]], [[immersion enhancement|immersion enhancing]], [[euphoric]], and mild [[entactogenic]] effects when [[Routes of administration|administered]]. The stimulating effects of NEP are believed to mainly be caused by its activity as a [[norepinephrine]]-[[dopamine]] [[reuptake inhibitor]] (NDRI); the reported ~~entactogenoc effectd~~ it displays may also be due to its activity as a [[serotonin]] [[reuptake inhibitor]] or [[releasing agent]] in moderate to high doses, although this has yet to be scientifically validated.{{citation needed}}

'''N-Ethyl-(nor)-pentedrone''' (also known as '''N-Ethylpentedrone''', '''Ethyl-pentedrone''' or more commonly, '''NEP''') is a novel synthetic [[psychoactive class::stimulant]] substance of the [[psychoactive class::cathinone]] chemical class that produces [[cathinone]]-like [[stimulating]], [[disinhibition|disinhibiting]], [[immersion enhancement|immersion enhancing]], [[euphoric]], and mild [[entactogenic]] effects when [[Routes of administration|administered]]. The stimulating effects of NEP are believed to mainly be caused by its activity as a [[norepinephrine]]-[[dopamine]] [[reuptake inhibitor]] (NDRI); the reported entactogenic effects it displays may also be due to its activity as a [[serotonin]] [[reuptake inhibitor]] or [[releasing agent]] in moderate to high doses, although this has yet to be scientifically validated.{{citation needed}}

NEP shares a close structural relationship to its parent compound [[pentedrone]], differing by an addition ethyl group on the terminal nitrogen on the carbon chain. This addition reportedly makes it about three times as potent as pentedrone.{{citation needed}} NEP is also closely related to [[N-Ethylhexedrone]] (commonly known as ''Hexen''), and has been reported as producing largely-similar effects.

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 {{SubstanceBox/N-Ethyl-(nor)-pentedrone}}
-'''N-Ethyl-(nor)-pentedrone''' (also known as '''N-Ethylpentedrone''', '''Ethyl-pentedrone''' or more commonly, '''NEP''') is a novel synthetic [[psychoactive class::stimulant]] substance of the [[psychoactive class::cathinone]] chemical class that produces [[cathinone]]-like [[stimulating]], [[disinhibition|disinhibiting]], [[immersion enhancement|immersion enhancing]], [[euphoric]], and mild [[entactogenic]] effects when [[Routes of administration|administered]]. The stimulating effects of NEP are believed to mainly be caused by its activity as a [[norepinephrine]]-[[dopamine]] [[reuptake inhibitor]] (NDRI); the reported entactogenoc effectd it displays may also be due to its activity as a [[serotonin]] [[reuptake inhibitor]] or [[releasing agent]] in moderate to high doses, although this has yet to be scientifically validated.{{citation needed}}
+'''N-Ethyl-(nor)-pentedrone''' (also known as '''N-Ethylpentedrone''', '''Ethyl-pentedrone''' or more commonly, '''NEP''') is a novel synthetic [[psychoactive class::stimulant]] substance of the [[psychoactive class::cathinone]] chemical class that produces [[cathinone]]-like [[stimulating]], [[disinhibition|disinhibiting]], [[immersion enhancement|immersion enhancing]], [[euphoric]], and mild [[entactogenic]] effects when [[Routes of administration|administered]]. The stimulating effects of NEP are believed to mainly be caused by its activity as a [[norepinephrine]]-[[dopamine]] [[reuptake inhibitor]] (NDRI); the reported entactogenic effects it displays may also be due to its activity as a [[serotonin]] [[reuptake inhibitor]] or [[releasing agent]] in moderate to high doses, although this has yet to be scientifically validated.{{citation needed}}
 NEP shares a close structural relationship to its parent compound [[pentedrone]], differing by an addition ethyl group on the terminal nitrogen on the carbon chain. This addition reportedly makes it about three times as potent as pentedrone.{{citation needed}} NEP is also closely related to [[N-Ethylhexedrone]] (commonly known as ''Hexen''), and has been reported as producing largely-similar effects.