3-MeO-PCE: Difference between revisions

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'''3-Methoxyeticyclidine''' (also known as '''Methoxieticyclidine''' and '''3-MeO-PCE''') is a novel synthetic [[Psychoactive class::dissociative]] substance of the [[Chemical class::arylcyclohexylamine]] chemical class~~. It~~ produces [[dissociative]], [[stimulating]] and [[hallucinogenic]] effects ~~that are reported to be very similar to those of its closely related analog, 3-MeO-PCP,~~ when [[Routes of administration|administered]].

'''3-Methoxyeticyclidine''' (also known as '''Methoxieticyclidine''' and '''3-MeO-PCE''') is a novel synthetic [[Psychoactive class::dissociative]] substance of the [[Chemical class::arylcyclohexylamine]] chemical class that produces [[dissociative]], [[stimulating]] and [[hallucinogenic]] effects when [[Routes of administration|administered]].

Early reports indicate that 3-MeO-PCE shares extremely similar properties to that of [[3-MeO-PCP]] and to a lesser extent, [[PCP]]/[[PCE]], [[MXE]] and [[O-PCE]]<ref>From PCP to MXE: a comprehensive review of the non-medical use of dissociative drugs | http://onlinelibrary.wiley.com/doi/10.1002/dta.1620/abstract</ref>, but with what seems to be a moderately higher risk of inducing states of [[delusions]], [[mania]] and [[psychosis]]. Because of this, it is highly recommended to use [[responsible drug use]] practices when using this substance such as using a [[milligram scale]] (and preferably [[volumetric liquid dosing]]) as well as having a sober [[trip sitter]] present throughout the experience.

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==Subjective effects==

3-MeO-PCE can be said to share extremely similar properties to that of [[3-MeO-PCP]] but with a ~~considerably~~ higher risk of inducing ~~serious~~ [[~~psychosis~~]], [[delusions]], and [[~~mania~~]] ~~which may make~~ it ~~dangerous~~ to ~~use regardless~~ of the ~~setting~~.

3-MeO-PCE can be said to share extremely similar properties to that of [[3-MeO-PCP]] but with a potentially higher risk of inducing states of [[mania]], [[delusions]] and potential [[psychosis]] due to the greater degree of euphoric [[stimulation]] and the [[compulsive redosing]] it can lead to. However, the effects are reported to largely converge with those of [[3-MeO-PCP]] after a certain dose-point, when the [[dissociating]] effects take over.

It is significantly more stimulating and less sedating than other [[~~dissociative~~]]s such as [[ketamine]] or [[MXE]]~~. It's far~~ more comfortable than [[O-PCE]], [[MXP]], [[diphenidine]] and other [[noradrenaline]] [[reuptake-~~inhibit~~]]~~ing~~ dissociative compounds which suggests that it may have a higher affinity for [[dopamine]] or [[serotonin]].

It is also often reported to be significantly more stimulating and less sedating than other [[dissociatives]] such as [[ketamine]] or [[MXE]] while more comfortable than [[O-PCE]], [[MXP]], [[diphenidine]] and other [[noradrenaline]] [[reuptake-inhibitor|reuptake inhibiting]] dissociative compounds which suggests that it may have a higher affinity for [[dopamine]] or [[serotonin]].{{citation needed}}

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 {{SubstanceBox/3-MeO-PCE}}
-'''3-Methoxyeticyclidine''' (also known as '''Methoxieticyclidine''' and '''3-MeO-PCE''') is a novel synthetic [[Psychoactive class::dissociative]] substance of the [[Chemical class::arylcyclohexylamine]] chemical class. It produces [[dissociative]], [[stimulating]] and [[hallucinogenic]] effects that are reported to be very similar to those of its closely related analog, 3-MeO-PCP, when [[Routes of administration|administered]].
+'''3-Methoxyeticyclidine''' (also known as '''Methoxieticyclidine''' and '''3-MeO-PCE''') is a novel synthetic [[Psychoactive class::dissociative]] substance of the [[Chemical class::arylcyclohexylamine]] chemical class that produces [[dissociative]], [[stimulating]] and [[hallucinogenic]] effects  when [[Routes of administration|administered]].
 Early reports indicate that 3-MeO-PCE shares extremely similar properties to that of [[3-MeO-PCP]] and to a lesser extent, [[PCP]]/[[PCE]], [[MXE]] and [[O-PCE]]<ref>From PCP to MXE: a comprehensive review of the non-medical use of dissociative drugs | http://onlinelibrary.wiley.com/doi/10.1002/dta.1620/abstract</ref>, but with what seems to be a moderately higher risk of inducing states of [[delusions]], [[mania]] and [[psychosis]]. Because of this, it is highly recommended to use [[responsible drug use]] practices when using this substance such as using a [[milligram scale]] (and preferably [[volumetric liquid dosing]]) as well as having a sober [[trip sitter]] present throughout the experience.
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 ==Subjective effects==
--MeO-PCE can be said to share extremely similar properties to that of [[3-MeO-PCP]] but with a considerably higher risk of inducing serious [[psychosis]], [[delusions]], and [[mania]] which may make it dangerous to use regardless of the setting.
+-MeO-PCE can be said to share extremely similar properties to that of [[3-MeO-PCP]] but with a potentially higher risk of inducing states of [[mania]], [[delusions]] and potential [[psychosis]] due to the greater degree of euphoric [[stimulation]] and the [[compulsive redosing]] it can lead to. However, the effects are reported to largely converge with those of [[3-MeO-PCP]] after a certain dose-point, when the [[dissociating]] effects take over.
-It is significantly more stimulating and less sedating than other [[dissociative]]s such as [[ketamine]] or [[MXE]]. It's far more comfortable than [[O-PCE]], [[MXP]], [[diphenidine]] and other [[noradrenaline]] [[reuptake-inhibit]]ing dissociative compounds which suggests that it may have a higher affinity for [[dopamine]] or [[serotonin]].
+It is also often reported to be significantly more stimulating and less sedating than other [[dissociatives]] such as [[ketamine]] or [[MXE]] while more comfortable than [[O-PCE]], [[MXP]], [[diphenidine]] and other [[noradrenaline]] [[reuptake-inhibitor|reuptake inhibiting]] dissociative compounds which suggests that it may have a higher affinity for [[dopamine]] or [[serotonin]].{{citation needed}}
 {{Preamble/SubjectiveEffects}}