PMMA: Difference between revisions

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{{headerpanel|{{Template:Warning/PMMA}} {{Approval~~}} {{Proofread~~}}}}

{{headerpanel|{{Template:Warning/PMMA}} {{Approval}}}}

{|

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| ''[[PMMA/Summary|Summary sheet: PMMA]]''

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'''~~PMMA~~''' ('''~~para~~-~~Methoxymethamphetamine~~'''~~, also known~~ as '''~~4-MMA~~''') is a highly dangerous and toxic ~~drug~~ of the [[Chemical class::~~Amphetamine|~~amphetamine]] class~~, which~~ is closely related to [[PMA]]. Like PMA, it ~~has~~ extremely dangerous side effects~~, which can result in death~~. At lower dosages, its effects are somewhat different from PMA, with reduced tendency to cause severe [[Increased bodily temperature|hyperthermia]] ~~and~~ producing more [[~~entactogen~~]]ic effects, although at higher dosages it does have the same risk as PMA. Its history of use is unknown, but it has appeared more frequently in the 2000s and 2010s. It is generally less potent than PMA.

'''para-Methoxymethamphetamine''' (also known as '''4-MMA''' and commonly as '''PMMA''') is a highly dangerous and toxic synthetic substance of the [[Chemical class::amphetamine]] class that is closely related to [[PMA]]. Like PMA, it is known for producing extremely dangerous, life-threatening side effects. At lower dosages, its effects are somewhat different from PMA, with reduced tendency to cause severe [[Increased bodily temperature|hyperthermia]] while producing more [[entactogenic]] effects that can be mistaken for [[MDMA]] (although at higher dosages it does have the same risk as PMA). Its history of use is unknown, but it has appeared more frequently in the 2000s and 2010s. It is generally less potent than PMA.

'''PMMA, along with other drugs like [[PMA]] and [[PMEA]] have very little recreational value and are considered as one of the most dangerous and toxic substances known. It is strongly recommended that these two ~~drugs should~~ be completely avoided.'''

'''PMMA, along with other drugs like [[PMA]] and [[PMEA]] have very little recreational value and are considered as one of the most dangerous and toxic substances known. It is strongly recommended that these two substancesshould be completely avoided.'''

==Chemistry==

PMMA (para-Methoxymethamphetamine or 4-MMA) is a molecule of the [[substituted ~~amphetamine|~~amphetamine]] class. Molecules of the amphetamine class contain a phenethylamine core featuring a phenyl ring bound to an amino (NH2) group through an ethyl chain with an additional methyl substitution at Rα. It contains a methoxy (OCH3) functional group bound to the R4 carbon of the phenyl ring, as well as a methyl substitution at RN. It is the methylated version of [[PMA]] and the 4-Methoxy analog of [[Methamphetamine]].

PMMA (para-Methoxymethamphetamine or 4-MMA) is a molecule of the [[substituted amphetamine]] class. Molecules of the amphetamine class contain a phenethylamine core featuring a phenyl ring bound to an amino (NH2) group through an ethyl chain with an additional methyl substitution at Rα. It contains a methoxy (OCH3) functional group bound to the R4 carbon of the phenyl ring, as well as a methyl substitution at RN. PMMA is the N-methylated version of [[PMA]] and the 4-Methoxy analog of [[Methamphetamine]].

==Pharmacology==

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*'''[[Effect::Increased heart rate]]'''

*'''[[Effect::Increased perspiration]]'''

*'''[[Effect::Nausea]]''' and '''~~vomiting~~''' - This is common at any dose.

*'''[[Effect::Nausea]]''' and '''Vomiting''' - This is common at any dose.

*'''[[Effect::Pupil dilation]]'''

*'''[[Effect::Rapid breathing]]''' - People commonly report "not being able to breathe".

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PMMA and its relative [[PMA]] [[Toxicity::can be considered extremely toxic when compared to other substances such as [[Methamphetamine]] or [[MDMA]] ]]. [[Toxicity::Ingestion of PMMA has been associated with severe tachycardia (abnormally high heart rate), [[seizure |seizures]], [[dehydration]], [[increased bodily temperature|hyperthermia]], and death]]. PMMA has a relatively slow onset, causing many users to redose which causes excess toxicity.

It is strongly recommended that one use [[~~responsible drug use|~~harm reduction practices]] ~~when using~~ this ~~drug~~.

It is strongly recommended that one use [[harm reduction practices]] if choosing to use this substance.

==~~Legal issues~~==

==Legality==

*'''Canada:''' PMMA is a Schedule I substance.

*'''Germany:''' PMMA is an Anlage I controlled substance.

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-{{headerpanel|{{Template:Warning/PMMA}} {{Approval}} {{Proofread}}}}
+{{headerpanel|{{Template:Warning/PMMA}} {{Approval}}}}
 {{SubstanceBox/PMMA}}
 {|
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 | ''[[PMMA/Summary|Summary sheet: PMMA]]''
 |}
-'''PMMA''' ('''para-Methoxymethamphetamine''', also known as '''4-MMA''') is a highly dangerous and toxic drug of the [[Chemical class::Amphetamine|amphetamine]] class, which is closely related to [[PMA]]. Like PMA, it has extremely dangerous side effects, which can result in death. At lower dosages, its effects are somewhat different from PMA, with reduced tendency to cause severe [[Increased bodily temperature|hyperthermia]] and producing more [[entactogen]]ic effects, although at higher dosages it does have the same risk as PMA. Its history of use is unknown, but it has appeared more frequently in the 2000s and 2010s. It is generally less potent than PMA.
+'''para-Methoxymethamphetamine''' (also known as '''4-MMA''' and commonly as '''PMMA''') is a highly dangerous and toxic synthetic substance of the [[Chemical class::amphetamine]] class that is closely related to [[PMA]]. Like PMA, it is known for producing extremely dangerous, life-threatening side effects. At lower dosages, its effects are somewhat different from PMA, with reduced tendency to cause severe [[Increased bodily temperature|hyperthermia]] while producing more [[entactogenic]] effects that can be mistaken for [[MDMA]] (although at higher dosages it does have the same risk as PMA). Its history of use is unknown, but it has appeared more frequently in the 2000s and 2010s. It is generally less potent than PMA.
-'''PMMA, along with other drugs like [[PMA]] and [[PMEA]] have very little recreational value and are considered as one of the most dangerous and toxic substances known. It is strongly recommended that these two drugs should be completely avoided.'''
+'''PMMA, along with other drugs like [[PMA]] and [[PMEA]] have very little recreational value and are considered as one of the most dangerous and toxic substances known. It is strongly recommended that these two substancesshould be completely avoided.'''
 ==Chemistry==
-PMMA (para-Methoxymethamphetamine or 4-MMA) is a molecule of the [[substituted amphetamine|amphetamine]] class. Molecules of the amphetamine class contain a phenethylamine core featuring a phenyl ring bound to an amino (NH<sub>2</sub>) group through an ethyl chain with an additional methyl substitution at R<sub>α</sub>. It contains a methoxy (OCH<sub>3</sub>) functional group bound to the R<sub>4</sub> carbon of the phenyl ring, as well as a methyl substitution at R<sub>N</sub>. It is the methylated version of [[PMA]] and the 4-Methoxy analog of [[Methamphetamine]].
+PMMA (para-Methoxymethamphetamine or 4-MMA) is a molecule of the [[substituted amphetamine]] class. Molecules of the amphetamine class contain a phenethylamine core featuring a phenyl ring bound to an amino (NH<sub>2</sub>) group through an ethyl chain with an additional methyl substitution at R<sub>α</sub>. It contains a methoxy (OCH<sub>3</sub>) functional group bound to the R<sub>4</sub> carbon of the phenyl ring, as well as a methyl substitution at R<sub>N</sub>. PMMA is the N-methylated version of [[PMA]] and the 4-Methoxy analog of [[Methamphetamine]].
 ==Pharmacology==
@@ Line 34: / Line 34: @@
 *'''[[Effect::Increased heart rate]]'''
 *'''[[Effect::Increased perspiration]]'''
-*'''[[Effect::Nausea]]''' and '''vomiting''' - This is common at any dose.
+*'''[[Effect::Nausea]]''' and '''Vomiting''' - This is common at any dose.
 *'''[[Effect::Pupil dilation]]'''
 *'''[[Effect::Rapid breathing]]''' - People commonly report "not being able to breathe".
@@ Line 65: / Line 65: @@
 PMMA and its relative [[PMA]] [[Toxicity::can be considered extremely toxic when compared to other substances such as [[Methamphetamine]] or [[MDMA]] ]]. [[Toxicity::Ingestion of PMMA has been associated with severe tachycardia (abnormally high heart rate), [[seizure |seizures]], [[dehydration]], [[increased bodily temperature|hyperthermia]], and death]]. PMMA has a relatively slow onset, causing many users to redose which causes excess toxicity.
-It is strongly recommended that one use [[responsible drug use|harm reduction practices]] when using this drug.
+It is strongly recommended that one use [[harm reduction practices]] if choosing to use this substance.
-==Legal issues==
+==Legality==
 *'''Canada:''' PMMA is a Schedule I substance.
 *'''Germany:''' PMMA is an Anlage I controlled substance.