Hexedrone: Difference between revisions

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~~{{headerpanel|{{approval}}}}~~

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'''Hexedrone''' is a novel synthetic [[psychoactive class::stimulant]] of the [[chemical category::cathinone]] chemical class that produces [[stimulation]], [[disinhibition]], [[thought acceleration]] and [[euphoria]] when [[Routes of administration|administered]]. Considering the close structurally similarities it share with [[pentedrone]], it has been speculated to act as a [[norepinephrine]]-[[dopamine]]-[[reuptake inhibitor|reuptake-inhibitor]] (NDRI). However, this has yet to be scientifically validated.

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~~| ''[[Hexedrone/Summary|Summary sheet: Hexedrone]]''~~

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'''Hexedrone''' is a [[~~research~~ chemical]] [[~~Stimulant|stimulant~~]] ~~that falls within the~~ [[~~Substituted cathinone~~|~~cathinone~~]] ~~category~~. Considering ~~its effects and its structure being closely related to~~ [[~~Pentedrone~~]], ~~this too is likely~~ to ~~be an~~ [[~~Norepinephrine~~]]-[[~~Dopamine~~]]-[[~~Reuptake~~ inhibitor|reuptake-inhibitor]] (NDRI). However, ~~these assumptions have not already been confirmed, due~~ to ~~insufficient research~~.

Due to ~~the lack~~ of ~~research along with only little experience-based~~ information, the ~~presented data might turn out to have some inaccuracies. This~~ should ~~especially~~ be ~~taken into consideration when interpreting the dosage information~~.

Little research exists about both hexedrone, particularly with regards to its toxicity, addiction, and abuse potential. Due to its novelty and extremely short history of human usage, all information related to the use of this compound should be treated with extreme caution.

==Chemistry==

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==Toxicity and harm potential==

Since hexedrone has been insufficiently studied and most data consists of speculation and user experiences, one should be cautious when it comes to the risks and harm~~. Especially long~~ term ~~effects could turn out to consist of serious~~ health hazards.

Since hexedrone has been insufficiently studied and most data consists of speculation and user experiences, one should be especially cautious when it comes to the risks and harm this substance may pose, especially in terms of seriouslong-term health hazards.

It is strongly recommended that one use [[responsible drug use|harm reduction practices]] when using this drug.

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===Tolerance and addiction potential===

As with other [[stimulant]]s, the chronic use of Hexedrone can be considered [[Addiction potential::moderately addictive with a high potential for abuse]] and is capable of causing psychological dependence among certain users. When addiction has developed, cravings and [[withdrawal effects]] may occur if a person suddenly stops their usage.

Tolerance to many of the effects of ~~Hexedrone~~ [[Time to full tolerance::develops with prolonged and repeated use]]. This results in users having to administer increasingly large doses to achieve the same effects. After that, it takes about [[Time to half tolerance::3 - 7 days]] for the tolerance to be reduced to half and [[Time to zero tolerance::1 - 2 weeks]] to be back at baseline (in the absence of further consumption). Hexedrone presents cross-tolerance with [[Cross-tolerance::all [[dopamine]]rgic [[stimulant]]s]], meaning that after the consumption of Hexedrone all [[stimulant]]s will have a reduced effect.

Tolerance to many of the effects of hexedrone [[Time to full tolerance::develops with prolonged and repeated use]]. This results in users having to administer increasingly large doses to achieve the same effects. After that, it takes about [[Time to half tolerance::3 - 7 days]] for the tolerance to be reduced to half and [[Time to zero tolerance::1 - 2 weeks]] to be back at baseline (in the absence of further consumption). Hexedrone presents cross-tolerance with [[Cross-tolerance::all [[dopamine]]rgic [[stimulant]]s]], meaning that after the consumption of Hexedrone all [[stimulant]]s will have a reduced effect.

==Legal issues==

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==See also==

*[[Responsible use]]

*[[Research chemical]]

*[[Stimulant]]

*[[Substituted cathinone~~|Cathinone~~]]

*[[Substituted cathinone]]

==External links==

*[https://en.wikipedia.org/wiki/Hexedrone Hexedrone (Wikipedia)]

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-{{headerpanel|{{approval}}}}
 {{distinguish2|[[N-Ethylhexedrone|N-Ethylhexedrone (Hexen)]]}}
 {{SubstanceBox/Hexedrone}}
-{|
+{{SummarySheet}}
-|-
+'''Hexedrone''' is a novel synthetic [[psychoactive class::stimulant]] of the [[chemical category::cathinone]] chemical class that produces [[stimulation]], [[disinhibition]], [[thought acceleration]] and [[euphoria]] when [[Routes of administration|administered]]. Considering the close structurally similarities it share with [[pentedrone]], it has been speculated to act as a [[norepinephrine]]-[[dopamine]]-[[reuptake inhibitor|reuptake-inhibitor]] (NDRI). However, this has yet to be scientifically validated.
-|-
-| ''[[Hexedrone/Summary|Summary sheet: Hexedrone]]''
-|}
-'''Hexedrone''' is a [[research chemical]] [[Stimulant|stimulant]] that falls within the [[Substituted cathinone|cathinone]] category. Considering its effects and its structure being closely related to [[Pentedrone]], this too is likely to be an [[Norepinephrine]]-[[Dopamine]]-[[Reuptake inhibitor|reuptake-inhibitor]] (NDRI). However, these assumptions have not already been confirmed, due to insufficient research.
-Due to the lack of research along with only little experience-based information, the presented data might turn out to have some inaccuracies. This should especially be taken into consideration when interpreting the dosage information.
+Little research exists about both hexedrone, particularly with regards to its toxicity, addiction, and abuse potential. Due to its novelty and extremely short history of human usage, all information related to the use of this compound should be treated with extreme caution.
 ==Chemistry==
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 ==Toxicity and harm potential==
 {{Further|Research chemicals#Toxicity and harm potential}}
-Since hexedrone has been insufficiently studied and most data consists of speculation and user experiences, one should be cautious when it comes to the risks and harm. Especially long term effects could turn out to consist of serious health hazards.
+Since hexedrone has been insufficiently studied and most data consists of speculation and user experiences, one should be especially cautious when it comes to the risks and harm this substance may pose, especially in terms of seriouslong-term  health hazards.
 It is strongly recommended that one use [[responsible drug use|harm reduction practices]] when using this drug.
-<!-- Yet another copy paste follows -->
 ===Tolerance and addiction potential===
 As with other [[stimulant]]s, the chronic use of Hexedrone can be considered [[Addiction potential::moderately addictive with a high potential for abuse]] and is capable of causing psychological dependence among certain users. When addiction has developed, cravings and [[withdrawal effects]] may occur if a person suddenly stops their usage.
-Tolerance to many of the effects of Hexedrone [[Time to full tolerance::develops with prolonged and repeated use]]. This results in users having to administer increasingly large doses to achieve the same effects. After that, it takes about [[Time to half tolerance::3 - 7 days]] for the tolerance to be reduced to half and [[Time to zero tolerance::1 - 2 weeks]] to be back at baseline (in the absence of further consumption). Hexedrone presents cross-tolerance with [[Cross-tolerance::all [[dopamine]]rgic [[stimulant]]s]], meaning that after the consumption of Hexedrone all [[stimulant]]s will have a reduced effect.
+Tolerance to many of the effects of hexedrone [[Time to full tolerance::develops with prolonged and repeated use]]. This results in users having to administer increasingly large doses to achieve the same effects. After that, it takes about [[Time to half tolerance::3 - 7 days]] for the tolerance to be reduced to half and [[Time to zero tolerance::1 - 2 weeks]] to be back at baseline (in the absence of further consumption). Hexedrone presents cross-tolerance with [[Cross-tolerance::all [[dopamine]]rgic [[stimulant]]s]], meaning that after the consumption of Hexedrone all [[stimulant]]s will have a reduced effect.
 ==Legal issues==
@@ Line 75: / Line 70: @@
 ==See also==
 *[[Responsible use]]
+*[[Research chemical]]
 *[[Stimulant]]
-*[[Substituted cathinone|Cathinone]]
+*[[Substituted cathinone]]
 ==External links==
 *[https://en.wikipedia.org/wiki/Hexedrone Hexedrone (Wikipedia)]