3-FEA: Difference between revisions

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'''3-Fluoroethamphetamine''' (also known as '''3-FEA''') is a novel synthetic ring-substituted fluorinated [[chemical class::amphetamine]] compound that produces a mixture of [[psychoactive class::entactogen|entactogenic]] and [[psychoactive class::stimulant|stimulating]] effects when [[Routes of administration|administered]]. 3-FEA is structurally related to a series of [[designer drug|designer]] fluorinated [[substituted amphetamine]]s that originally included compounds such as [[2-FA]], [[2-FMA]], [[3-FA]], [[4-FMA]], [[4-FA]].<ref>Quednow, B., Girreser, U., Junge, T., & Ro, P. (2005). Isomeric Fluoro-methoxy-phenylalkylamines: a new series of controlled-substance analogues (designer drugs), 148, 143–156. https://doi.org/10.1016/j.forsciint.2004.05.003</ref>
'''3-Fluoroethamphetamine''' (also known as '''3-FEA''') is a novel synthetic ring-substituted fluorinated [[chemical class::amphetamine]] compound that produces a mixture of [[psychoactive class::entactogen|entactogenic]] and [[psychoactive class::stimulant|stimulating]] effects when [[Routes of administration|administered]]. 3-FEA is structurally related to a series of [[designer drug|designer]] fluorinated [[substituted amphetamine]]s that originally included compounds such as [[2-FA]], [[2-FMA]], [[3-FA]], [[4-FMA]], [[4-FA]].<ref>Quednow, B., Girreser, U., Junge, T., & Ro, P. (2005). Isomeric Fluoro-methoxy-phenylalkylamines: a new series of controlled-substance analogues (designer drugs), 148, 143–156. https://doi.org/10.1016/j.forsciint.2004.05.003</ref>


Like its parent compound [[3-FA]], the pharmacological, toxicological, and subjective effects of 3-FEA in humans have yet to be mapped out in detail. Early reports have so far characterized 3-FEA as a moderately potent [[serotonin]] and [[norepinephrine]]-dominant triple [[monoamine]] [[releaser]] or [[reuptake inhibitor]] that produces a unique balance of [[entactogenic]] and [[stimulant]] effects that skews more to the recreational-euphoric side (similar to one of its popular predecessors, [[4-FA]]), than towards what some consider to be "functional" or "productivity-enhancing" (e.g. [[amphetamine]], [[2-FA]], [[methylphenidate]]).  
Like its parent compound [[3-FA]], the pharmacological, toxicological, and subjective effects of 3-FEA in humans have yet to be mapped out in detail. Early reports have so far characterized 3-FEA as a moderately potent [[serotonin]] and [[norepinephrine]]-dominant triple [[monoamine]] [[releaser]] or [[reuptake inhibitor]] that produces a unique balance of [[entactogenic]] and [[stimulant]] effects that skews more to the recreational-euphoric side (similar to one of its popular predecessors, [[4-FA]]), than towards what some consider to be "functional" or "productivity-enhancing" (e.g. [[amphetamine]], [[2-FA]], and [[methylphenidate]]).  
   
   
3-FEA has an extremely short history of human [[recreational drug use|recreational use]] and has yet to be documented being sold on the streets.  It has recently been made available for sale on the gray market as a [[research chemical]] by online vendors.{{citation needed}} It should be noted that based on the pharmacology activity displayed by structurally related compounds such as [https://en.wikipedia.org/wiki/Fenfluramine fenfluramine], it is not unlikely that this compound may possess neurotoxic, cardiotoxic and other [[research chemical|potential to-be-discovered toxic properties]]{{citation needed}}.  
3-FEA has an extremely short history of human [[recreational drug use|recreational use]] and has yet to be documented being sold on the streets.  It has recently been made available for sale on the gray market as a [[research chemical]] by online vendors.{{citation needed}} It should be noted that based on the pharmacology activity displayed by structurally related compounds such as [https://en.wikipedia.org/wiki/Fenfluramine fenfluramine], it is not unlikely that this compound may possess neurotoxic, cardiotoxic and other [[research chemical|potential to-be-discovered toxic properties]]{{citation needed}}.  
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