APICA: Difference between revisions

2NE1, or N-(1-adamantyl)-1-pentyl-1H-indole-3-carboxamide, is a synthetic [[Chemical class::indole cannabinoid]] as it contains a substituted indole group. This indole moeity is substituted at R₁ with a pentyl chain, a substitution shared with [[JWH-018]]. Additionally, the indole is substituted at R₃ with a carboxamide group.  This carboxamide group is N-substituted at its terminal amine group with an adamantane group. This group consists of four fused cyclohexane rings in a unique structure called a diamondoid. 2NE1 can be considered the indole analogue of [[AKB48]] and the pentyl analogue of [[STS-135]].