Serotonin: Difference between revisions

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'''Serotonin''', also known as '''5-hydroxytryptamine''' ('''5-HT'''), is a monoamine [[neurotransmitter|neurotransmitter]] affecting the [[serotonin]] [[receptors]] (5-HT<sub>1-7</sub>). Serotonin is primarily found in the gastrointestinal tract, platelets, and in the central nervous system of animals including humans. It is popularly thought to be a contributor to feelings of well-being and happiness.

Approximately 90% of the human body's total serotonin is located in the digestive system, where it is used to regulate intestinal movements. The remainder is synthesized in serotonergic [[~~neurone~~|~~neurones~~]] of the CNS, where it has various functions. These include the regulation of mood, appetite, and sleep. Serotonin also has some cognitive functions, including memory and learning. In the blood, it serves as a [[vasoconstriction|vasoconstrictor]], and could be attributed as the cause of vasoconstriction in most serotonergic drugs.

Approximately 90% of the human body's total serotonin is located in the digestive system, where it is used to regulate intestinal movements. The remainder is synthesized in serotonergic [[neuron|neurons]] of the CNS, where it has various functions. These include the regulation of mood, appetite, and sleep. Serotonin also has some cognitive functions, including memory and learning. In the blood, it serves as a [[vasoconstriction|vasoconstrictor]], and could be attributed as the cause of vasoconstriction in most serotonergic drugs.

==Chemistry==

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==The 5-HT system==

The 5-HT receptors, or serotonin receptors, are found in the central nervous system and the peripheral nervous system. They exhibit both excitatory and inhibitory [[~~neurone~~#neurotransmission|neurotransmission]].

The 5-HT receptors, or serotonin receptors, are found in the central nervous system and the peripheral nervous system. They exhibit both excitatory and inhibitory [[neuron#neurotransmission|neurotransmission]].

===Drugs targeting the 5-HT system===

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 '''Serotonin''', also known as '''5-hydroxytryptamine''' ('''5-HT'''), is a monoamine [[neurotransmitter|neurotransmitter]] affecting the [[serotonin]] [[receptors]] (5-HT<sub>1-7</sub>). Serotonin is primarily found in the gastrointestinal tract, platelets, and in the central nervous system of animals including humans. It is popularly thought to be a contributor to feelings of well-being and happiness.
-Approximately 90% of the human body's total serotonin is located in the digestive system, where it is used to regulate intestinal movements. The remainder is synthesized in serotonergic [[neurone|neurones]] of the CNS, where it has various functions. These include the regulation of mood, appetite, and sleep. Serotonin also has some cognitive functions, including memory and learning. In the blood, it serves as a [[vasoconstriction|vasoconstrictor]], and could be attributed as the cause of vasoconstriction in most serotonergic drugs.
+Approximately 90% of the human body's total serotonin is located in the digestive system, where it is used to regulate intestinal movements. The remainder is synthesized in serotonergic [[neuron|neurons]] of the CNS, where it has various functions. These include the regulation of mood, appetite, and sleep. Serotonin also has some cognitive functions, including memory and learning. In the blood, it serves as a [[vasoconstriction|vasoconstrictor]], and could be attributed as the cause of vasoconstriction in most serotonergic drugs.
 ==Chemistry==
@@ Line 10: / Line 10: @@
 ==The 5-HT system==
-The 5-HT receptors, or serotonin receptors, are found in the central nervous system and the peripheral nervous system. They exhibit both excitatory and inhibitory [[neurone#neurotransmission|neurotransmission]].
+The 5-HT receptors, or serotonin receptors, are found in the central nervous system and the peripheral nervous system. They exhibit both excitatory and inhibitory [[neuron#neurotransmission|neurotransmission]].
 ===Drugs targeting the 5-HT system===