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Talk:Dextrorphan: Difference between revisions
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==Chemistry== | ==Chemistry== | ||
[[DXM]] is metabolized in the body by o-demethylation through the CYP2D6 enzyme to form DXO. Both are active chemicals and contribute to the [[DXM#Subjective effects|subjective effects]] experienced when active doses of DXM are consumed.<ref>Dextromethorphan: An update on its utility for neurological and neuropsychiatric disorders - 3. Pharmacodynamics (January 2016)[https://www.researchgate.net/publication/292212463_Dextromethorphan_An_update_on_its_utility_for_neurological_and_neuropsychiatric_disorders]</ref> | [[DXM]] is metabolized in the body by o-demethylation through the CYP2D6 enzyme to form DXO.<ref>Cytochrome P450-dependent metabolism of dextromethorphan: fetal and adult studies. [https://www.ncbi.nlm.nih.gov/pubmed/1306804]</ref> Both are active chemicals and contribute to the [[DXM#Subjective effects|subjective effects]] experienced when active doses of DXM are consumed.<ref>Dextromethorphan: An update on its utility for neurological and neuropsychiatric disorders - 3. Pharmacodynamics (January 2016)[https://www.researchgate.net/publication/292212463_Dextromethorphan_An_update_on_its_utility_for_neurological_and_neuropsychiatric_disorders]</ref> | ||
==Pharmacology== | ==Pharmacology== | ||