Piracetam: Difference between revisions

Line 53:

Adverse effects, although rare and of short duration are limited to [[anxiety]], [[wakefulness|insomnia]], [[sedation|drowsiness]] and [[irritability|agitation]]. It may be safe for up to 18 months in humans at doses of 3.2g daily with one year-long study in ambulatory patients with Alzheimer's using 8g daily reporting no side effects.<ref>Long-term efficacy and safety of piracetam in the treatment of progressive myoclonus epilepsy. | http://www.ncbi.nlm.nih.gov/pubmed/11346373</ref> However, a possibility for adverse drug-drug interactions persists for piracetam due to it interacting with blood in an anti-clotting manner (and such, caution should be taken when pairing piracetam with pharmaceutical blood thinning agents such as Warfarin or potent nutraceutical options).

No fatal overdoses associated with piracetam use have been reported as of 2016. In animal models (rodents, dogs, and marmoset), an [[LD50]] failed to be established at the dosage of 8-10g/kg.

No fatal overdoses associated with piracetam use have been reported as of 2016. In animal models (rodents, dogs, and marmoset), an [[LD50|LD<sub>50</sub>]] failed to be established at the dosage of 8-10g/kg.

Regardless, it is strongly recommended that one use [[responsible drug use|harm reduction practices]] when using this drug.

@@ Line 53: / Line 53: @@
 Adverse effects, although rare and of short duration are limited to [[anxiety]], [[wakefulness|insomnia]], [[sedation|drowsiness]] and [[irritability|agitation]]. It may be safe for up to 18 months in humans at doses of 3.2g daily with one year-long study in ambulatory patients with Alzheimer's using 8g daily reporting no side effects.<ref>Long-term efficacy and safety of piracetam in the treatment of progressive myoclonus epilepsy. | http://www.ncbi.nlm.nih.gov/pubmed/11346373</ref> However, a possibility for adverse drug-drug interactions persists for piracetam due to it interacting with blood in an anti-clotting manner (and such, caution should be taken when pairing piracetam with pharmaceutical blood thinning agents such as Warfarin or potent nutraceutical options).
-No fatal overdoses associated with piracetam use have been reported as of 2016. In animal models (rodents, dogs, and marmoset), an [[LD50]] failed to be established at the dosage of 8-10g/kg.
+No fatal overdoses associated with piracetam use have been reported as of 2016. In animal models (rodents, dogs, and marmoset), an [[LD50|LD<sub>50</sub>]] failed to be established at the dosage of 8-10g/kg.
 Regardless, it is strongly recommended that one use [[responsible drug use|harm reduction practices]] when using this drug.