NEP: Difference between revisions

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| ''[[N-Ethyl-(nor)-~~Pentedrone~~/Summary|Summary sheet: N-Ethyl-(nor)-~~Pentedrone~~]]''

| ''[[N-Ethyl-(nor)-pentedrone/Summary|Summary sheet: N-Ethyl-(nor)-pentedrone]]''

|}

'''N-Ethyl-(nor)-~~Pentedrone~~''' (also known as '''N-~~Ethyl-Pentedrone~~''' or '''NEP''') is a [[psychoactive class::stimulant]] belonging to the [[~~Substituted cathinone|~~cathinone]] class. Ethyl-pentedrone's stimulation is believed to be caused by its affinity as an NDRI ([[norepinephrine]]-[[dopamine]] reuptake inhibitor); however, there have been no scientific studies confirming this. It may also act as a serotonin reuptake inhibitor or releasing agent in moderate to high doses, ~~but~~ this is only speculation.

'''N-Ethyl-(nor)-pentedrone''' (also known as '''N-Ethylpentedrone''' or more commonly, '''NEP''') is a novel synthetic [[psychoactive class::stimulant]] compound belonging to the substituted [[psychoactive class::cathinone]] class. N-Ethyl-(nor)-pentedrone's stimulation is believed to be caused by its affinity as an NDRI ([[norepinephrine]]-[[dopamine]] reuptake inhibitor); however, there have been no scientific studies confirming this. It may also act as a serotonin reuptake inhibitor or releasing agent in moderate to high doses, although this is only speculation.

Ethyl-pentedrone is closely related to [[pentedrone]], with an added ethyl-group on the carbon chain containing the nitrogen. This addition makes it about 3x as potent as pentedrone. ~~Ethyl~~-pentedrone is also closely related to ~~ethyl~~-~~hexedrone~~, and ~~is likely very~~ similar in ~~effects~~.

N-Ethyl-(nor)-pentedrone is closely related to [[pentedrone]], with an added ethyl group on the carbon chain containing the nitrogen. This addition makes it about 3x as potent as pentedrone.{{citation needed}} N-ethyl-(nor)-pentedrone is also closely related to [[N-Ethylhexedrone]] (commonly known as ''Hexen''), and has been reported as being similar in effect.

Ethyl-pentedrone first became known in the [[research chemical]] market during 2016. Little research exists about ethyl-pentedrone and its parent compound pentedrone. All dosage information found on the internet should be treated with caution.

N-Ethyl-(nor)-pentedrone first became known in the [[research chemical]] market during 2016. Little research exists about both N-ethyl-(nor)-pentedrone and its parent compound [[pentedrone]]. All dosage information found on the internet should be treated with caution. It is an example of a contemporary [[designer drug]] specifically chosen to mimic/replace the functional and structural features of its popular potent and short-lived-type stimulant predecessors, which are sometimes imprecisely referred to as "bath salts". Little research exists about N-ethyl-(nor)-pentedrone as well as its parent compound [[pentedrone]], particularly with regards to its toxicity, addiction and abuse potential. Due to its novelty and extremely short history of human usage, all information related to the use of this compound should be treated with extreme caution. It is strongly recommended that one use [[responsible drug use|harm reduction practices]] when choosing to use this substance.

==Chemistry==

Ethyl-pentedrone is a [[Substituted cathinone|cathinone]], which means that it features a [[phenethylamine]] core with an alkyl group attached to the alpha carbon and an oxygen group attached to the beta carbon. Cathinones are beta-ketone analogues of [[amphetamine]]s.

N-Ethyl-(nor)-pentedrone is a [[Substituted cathinone|cathinone]], which means that it features a [[phenethylamine]] core with an alkyl group attached to the alpha carbon and an oxygen group attached to the beta carbon. Cathinones are beta-ketone analogues of [[amphetamine]]s.

==Pharmacology==

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-{{Template:SubstanceBox/N-Ethyl-(nor)-Pentedrone}}
+{{Template:SubstanceBox/N-Ethyl-(nor)-pentedrone}}
 {|
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-| ''[[N-Ethyl-(nor)-Pentedrone/Summary|Summary sheet: N-Ethyl-(nor)-Pentedrone]]''
+| ''[[N-Ethyl-(nor)-pentedrone/Summary|Summary sheet: N-Ethyl-(nor)-pentedrone]]''
 |}
-'''N-Ethyl-(nor)-Pentedrone''' (also known as '''N-Ethyl-Pentedrone''' or '''NEP''') is a [[psychoactive class::stimulant]] belonging to the [[Substituted cathinone|cathinone]] class. Ethyl-pentedrone's stimulation is believed to be caused by its affinity as an NDRI ([[norepinephrine]]-[[dopamine]] reuptake inhibitor); however, there have been no scientific studies confirming this. It may also act as a serotonin reuptake inhibitor or releasing agent in moderate to high doses, but this is only speculation.
+'''N-Ethyl-(nor)-pentedrone''' (also known as '''N-Ethylpentedrone''' or more commonly, '''NEP''') is a novel synthetic [[psychoactive class::stimulant]] compound belonging to the substituted [[psychoactive class::cathinone]] class. N-Ethyl-(nor)-pentedrone's stimulation is believed to be caused by its affinity as an NDRI ([[norepinephrine]]-[[dopamine]] reuptake inhibitor); however, there have been no scientific studies confirming this. It may also act as a serotonin reuptake inhibitor or releasing agent in moderate to high doses, although this is only speculation.
-Ethyl-pentedrone is closely related to [[pentedrone]], with an added ethyl-group on the carbon chain containing the nitrogen. This addition makes it about 3x as potent as pentedrone. Ethyl-pentedrone is also closely related to ethyl-hexedrone, and is likely very similar in effects.
+N-Ethyl-(nor)-pentedrone is closely related to [[pentedrone]], with an added ethyl group on the carbon chain containing the nitrogen. This addition makes it about 3x as potent as pentedrone.{{citation needed}} N-ethyl-(nor)-pentedrone is also closely related to [[N-Ethylhexedrone]] (commonly known as ''Hexen''), and has been reported as being similar in effect.
-Ethyl-pentedrone first became known in the [[research chemical]] market during 2016. Little research exists about ethyl-pentedrone and its parent compound pentedrone. All dosage information found on the internet should be treated with caution.
+N-Ethyl-(nor)-pentedrone first became known in the [[research chemical]] market during 2016. Little research exists about both N-ethyl-(nor)-pentedrone and its parent compound [[pentedrone]]. All dosage information found on the internet should be treated with caution. It is an example of a contemporary [[designer drug]] specifically chosen to mimic/replace the functional and structural features of its popular potent and short-lived-type stimulant predecessors, which are sometimes imprecisely referred to as "bath salts". Little research exists about N-ethyl-(nor)-pentedrone as well as its parent compound [[pentedrone]], particularly with regards to its toxicity, addiction and abuse potential. Due to its novelty and extremely short history of human usage, all information related to the use of this compound should be treated with extreme caution. It is strongly recommended that one use [[responsible drug use|harm reduction practices]] when choosing to use this substance.
 ==Chemistry==
-Ethyl-pentedrone is a [[Substituted cathinone|cathinone]], which means that it features a [[phenethylamine]] core with an alkyl group attached to the alpha carbon and an oxygen group attached to the beta carbon. Cathinones are beta-ketone analogues of [[amphetamine]]s.
+N-Ethyl-(nor)-pentedrone is a [[Substituted cathinone|cathinone]], which means that it features a [[phenethylamine]] core with an alkyl group attached to the alpha carbon and an oxygen group attached to the beta carbon. Cathinones are beta-ketone analogues of [[amphetamine]]s.
 ==Pharmacology==