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MDPV: Difference between revisions
>BronzeManul m Added to Pyrrolidine category and added link to Substituted pyrrolidine page. |
>BronzeManul m Replaced mentions of a pyrovalerone chemical class with the pyrrolidine chemical class. |
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| ''[[MDPV/Summary|Summary sheet: MDPV]]'' | | ''[[MDPV/Summary|Summary sheet: MDPV]]'' | ||
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'''MDPV''' ('''3,4-Methylenedioxypyrovalerone'''; also known as '''Bath Salts''', and '''NRG-1''' among others) is a synthetic [[psychoactive class::stimulant]] drug of the [[ | '''MDPV''' ('''3,4-Methylenedioxypyrovalerone'''; also known as '''Bath Salts''', and '''NRG-1''' among others) is a synthetic [[psychoactive class::stimulant]] drug of the [[substituted cathinone|cathinone]] and [[substituted pyrrolidine|pyrrolidine]] chemical classes. MDPV is thought to act primarily as as a [[norepinephrine]]-[[dopamine]] [[reuptake inhibitor]] (NDRI) and possesses powerful euphoric [[stimulant]] qualities. It was first developed in the 1960s by a team at Boehringer Ingelheim.<ref>US Patent 3478050 - 1-(3',4'-methylenedioxy-phenyl)-2-pyrrolidino-alkanones-(1) | https://www.google.com/patents/US3478050</ref> | ||
MDPV remained an obscure stimulant until around 2004, when it was reportedly first made available to the public as a [[designer drug]]. Products labeled as "bath salts" containing MDPV were previously sold as recreational drugs in gas stations and convenience stores in the United States, similar to the marketing strategy of [[Synthetic cannabinoids|Spice and K2]] as incense. | MDPV remained an obscure stimulant until around 2004, when it was reportedly first made available to the public as a [[designer drug]]. Products labeled as "bath salts" containing MDPV were previously sold as recreational drugs in gas stations and convenience stores in the United States, similar to the marketing strategy of [[Synthetic cannabinoids|Spice and K2]] as incense. | ||
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==Chemistry== | ==Chemistry== | ||
MDPV, or 3,4-Methylenedioxypyrovalerone, is a synthetic stimulant of the [[ | MDPV, or 3,4-Methylenedioxypyrovalerone, is a synthetic stimulant of the [[substituted cathinone|cathinone]] and [[substituted pyrrolidine|pyrrolidine]] classes. MDPV is the 3,4-methylenedioxy ring-substituted analog of the compound [[a-PVP]], developed in the 1960s, which has been used for the treatment of chronic fatigue and as an anorectic, but caused problems of abuse and dependence.<ref>US Patent 3478050 - 1-(3',4'-methylenedioxy-phenyl)-2-pyrrolidino-alkanones-(1) | https://www.google.com/patents/US3478050</ref> However, despite some shared structural features, the effects of MDPV bear little resemblance to other methylenedioxy phenylalkylamine derivatives such as 3,4-methylenedioxy-N-methylamphetamine ([[MDMA]]), instead producing primarily classical stimulant effects with only mild entactogenic qualities.<ref>MDPV | https://wiki.tripsit.me/wiki/MDPV</ref> | ||
==Pharmacology== | ==Pharmacology== | ||