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Hexedrone: Difference between revisions
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==Pharmacology== | ==Pharmacology== | ||
Due to the lack of research regarding the substance, all discussion regarding the pharmacology of it is purely | Due to the lack of research regarding the substance, all discussion regarding the pharmacology of it is purely based upon its structure and subjective effect similarities to other [[Substituted cathinone|cathinone]]s such as [[Pentedrone|pentedrone]] and others. Hexedrone most likely acts as both a [[dopamine]] and [[norepinephrine]] [[reuptake inhibitor]]. This allows [[Dopamine|dopamine]] and [[Norepinephrine|norepinephrine]] to build up within the brain, resulting in [[stimulation|stimulating]] and [[physical euphoria|euphoric]] effects. | ||
The decreased potency, compared to both pentedrone as well as [[Ethyl-Hexedrone|ethyl-hexedrone]] can be easily explained. Compared to pentedrone, there's a larger non-polar side chain. Ethyl-hexedrone has an ethyl group, instead of a methyl, which results in a significantly shifted electronegativity. | The decreased potency, compared to both pentedrone as well as [[Ethyl-Hexedrone|ethyl-hexedrone]] can be easily explained. Compared to pentedrone, there's a larger non-polar side chain. Ethyl-hexedrone has an ethyl group, instead of a methyl, which results in a significantly shifted electronegativity. | ||
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{{Main|Research chemicals#Toxicity and harm potential}} | {{Main|Research chemicals#Toxicity and harm potential}} | ||
Since hexedrone has been insufficiently studied and most data consists of speculation and user experiences, one should be cautious when it comes to the risks and harm. Especially long term effects could turn out to consist of serious health hazards. | Since hexedrone has been insufficiently studied and most data consists of speculation and user experiences, one should be cautious when it comes to the risks and harm. Especially long term effects could turn out to consist of serious health hazards. | ||
It is strongly recommended that one use [[responsible | It is strongly recommended that one use [[responsible drug use|harm reduction practices]] when using this drug. | ||
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==Legal issues== | ==Legal issues== | ||
{{LegalStub}} | {{LegalStub}} | ||
*'''UK''' - In the UK, Hexedrone is a Class B | *'''UK''' - In the UK, Hexedrone is a Class B drug under The Misuse of Drugs Act 1971 (Amendment) Order 2010 following the ACMD's report on substituted cathinone derivatives,<ref>https://www.gov.uk/government/uploads/system/uploads/attachment_data/file/119173/acmd-cathinodes-report-2010.pdf</ref> making it illegal to sell, buy, or possess without a license.<ref>http://webarchive.nationalarchives.gov.uk/20130125102358/http://www.homeoffice.gov.uk/about-us/corporate-publications-strategy/home-office-circulars/circulars-2010/010-2010/</ref><ref>http://www.legislation.gov.uk/uksi/2010/1207/article/2/made</ref> | ||
==See also== | ==See also== | ||