SAM-e: Difference between revisions

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Sam-e is also hypothesized to raise homocystine to harmful levels, but this has yet to be proven in a laboratory environment. <ref>Influence of oral S-adenosylmethionine on plasma 5-methyltetrahydrofolate, S-adenosylhomocysteine, homocysteine and methionine in healthy humans. | http://www.ncbi.nlm.nih.gov/pubmed/9262350</ref> Still, it is advised to take Sam-e along with folate and B12.

Regardless, it is strongly recommended that one be familiar with [[responsible ~~substance~~ use|harm reduction practices]] when using Sam-e.

Regardless, it is strongly recommended that one be familiar with [[responsible drug use|harm reduction practices]] when using Sam-e.

===Tolerance and addiction potential===

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*'''United States''' - Sam-e is approved and legal over the counter for purchase.

*'''Russia''' - Sam-e is available by prescription.

*'''United Kingdom''' - It is illegal to produce, supply, or import this ~~substance~~ under the Psychoactive Substance Act, which came into effect on May 26th, 2016.<ref>Psychoactive Substances Act 2016 (Legislation.gov.uk) | http://www.legislation.gov.uk/ukpga/2016/2/contents/enacted</ref>

*'''United Kingdom''' - It is illegal to produce, supply, or import this drug under the Psychoactive Substance Act, which came into effect on May 26th, 2016.<ref>Psychoactive Substances Act 2016 (Legislation.gov.uk) | http://www.legislation.gov.uk/ukpga/2016/2/contents/enacted</ref>

==See also==

@@ Line 60: / Line 60: @@
 Sam-e is also hypothesized to raise homocystine to harmful levels, but this has yet to be proven in a laboratory environment. <ref>Influence of oral S-adenosylmethionine on plasma 5-methyltetrahydrofolate, S-adenosylhomocysteine, homocysteine and methionine in healthy humans. | http://www.ncbi.nlm.nih.gov/pubmed/9262350</ref> Still, it is advised to take Sam-e along with folate and B12.
-Regardless, it is strongly recommended that one be familiar with [[responsible substance use|harm reduction practices]] when using Sam-e.
+Regardless, it is strongly recommended that one be familiar with [[responsible drug use|harm reduction practices]] when using Sam-e.
 ===Tolerance and addiction potential===
@@ Line 70: / Line 70: @@
 *'''United States''' - Sam-e is approved and legal over the counter for purchase.
 *'''Russia''' - Sam-e is available by prescription.
-*'''United Kingdom''' - It is illegal to produce, supply, or import this substance under the Psychoactive Substance Act, which came into effect on May 26th, 2016.<ref>Psychoactive Substances Act 2016 (Legislation.gov.uk) | http://www.legislation.gov.uk/ukpga/2016/2/contents/enacted</ref>
+*'''United Kingdom''' - It is illegal to produce, supply, or import this drug under the Psychoactive Substance Act, which came into effect on May 26th, 2016.<ref>Psychoactive Substances Act 2016 (Legislation.gov.uk) | http://www.legislation.gov.uk/ukpga/2016/2/contents/enacted</ref>
 ==See also==