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SAM-e: Difference between revisions
>Kenan m Text replacement - "The effects listed below are based upon the subjective effects index and personal experiences of PsychonautWiki contributors. The listed effects will rarely (if ever) occur all at once, but heavier dosages will increase the chances and are more likely to induce a full range of effects." to "{{Preamble/SubjectiveEffects}}" |
>Kaylee m Text replacement - " drug " to " substance " |
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Sam-e is also hypothesized to raise homocystine to harmful levels, but this has yet to be proven in a laboratory environment. <ref>Influence of oral S-adenosylmethionine on plasma 5-methyltetrahydrofolate, S-adenosylhomocysteine, homocysteine and methionine in healthy humans. | http://www.ncbi.nlm.nih.gov/pubmed/9262350</ref> Still, it is advised to take Sam-e along with folate and B12. | Sam-e is also hypothesized to raise homocystine to harmful levels, but this has yet to be proven in a laboratory environment. <ref>Influence of oral S-adenosylmethionine on plasma 5-methyltetrahydrofolate, S-adenosylhomocysteine, homocysteine and methionine in healthy humans. | http://www.ncbi.nlm.nih.gov/pubmed/9262350</ref> Still, it is advised to take Sam-e along with folate and B12. | ||
Regardless, it is strongly recommended that one be familiar with [[responsible | Regardless, it is strongly recommended that one be familiar with [[responsible substance use|harm reduction practices]] when using Sam-e. | ||
===Tolerance and addiction potential=== | ===Tolerance and addiction potential=== | ||
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*'''United States''' - Sam-e is approved and legal over the counter for purchase. | *'''United States''' - Sam-e is approved and legal over the counter for purchase. | ||
*'''Russia''' - Sam-e is available by prescription. | *'''Russia''' - Sam-e is available by prescription. | ||
*'''United Kingdom''' - It is illegal to produce, supply, or import this | *'''United Kingdom''' - It is illegal to produce, supply, or import this substance under the Psychoactive Substance Act, which came into effect on May 26th, 2016.<ref>Psychoactive Substances Act 2016 (Legislation.gov.uk) | http://www.legislation.gov.uk/ukpga/2016/2/contents/enacted</ref> | ||
==See also== | ==See also== | ||