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25I-NBOMe: Difference between revisions
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25I-NBOMe is a relatively new substance, and little is known about its pharmacological risks or its interaction with other substances. The [[LD50]] has not yet been determined although it is [[Toxicity::potentially fatal at heavy dosages]].<ref name="Fatalities / Deaths"> "Fatalities / Deaths". Erowid. April 26 2013. Retrieved 7 May 2013. | http://www.erowid.org/chemicals/2ci_nbome/2ci_nbome_death.shtml</ref> [[PsychonautWiki]] advises that due to 25I-NBOMe's extreme potency it should not be insufflated as this method of administration appears to have led to several deaths in the past year.<ref>http://www.erowid.org/chemicals/2ci_nbome/2ci_nbome.shtml/</ref> | 25I-NBOMe is a relatively new substance, and little is known about its pharmacological risks or its interaction with other substances. The [[LD50]] has not yet been determined although it is [[Toxicity::potentially fatal at heavy dosages]].<ref name="Fatalities / Deaths"> "Fatalities / Deaths". Erowid. April 26 2013. Retrieved 7 May 2013. | http://www.erowid.org/chemicals/2ci_nbome/2ci_nbome_death.shtml</ref> [[PsychonautWiki]] advises that due to 25I-NBOMe's extreme potency it should not be insufflated as this method of administration appears to have led to several deaths in the past year.<ref>http://www.erowid.org/chemicals/2ci_nbome/2ci_nbome.shtml/</ref> | ||
This substance came to media attention in early 2012 after a cluster of seven non-fatal [[overdose]]s with the | This substance came to media attention in early 2012 after a cluster of seven non-fatal [[overdose]]s with the substance were reported in or around Richmond, Virginia.<ref name="Kids overdosing on new drug"> "Kids overdosing on new drug. Laura Geller, WWBT NBC12, Feb 18, 2012 | http://www.nbc12.com/story/16964534/kids-overdosing-on-new-drug</ref><ref name="New street drug"> New street substance causing concern among medics. Vanessa Araiza, WBRC, Feb 28, 2012 | http://www.wsfa.com/story/16977573/new-street-drug-causing-concern-among-medics</ref> As of May 2013, 25I-NBOMe has reportedly led to five overdose deaths in the United States.<ref name="NY Daily news"> New substance N-bomb hits the street, terrifying parents, troubling cops | http://www.nydailynews.com/news/national/new-synthetic-hallucinogen-n-bomb-killing-users-cops-article-1.1336327</ref> In June 2012, two teens in Grand Forks, North Dakota and East Grand Forks, Minnesota fatally overdosed on a substance that was allegedly 25I-NBOMe, resulting in lengthy sentences for two of the parties involved and a Federal indictment against the Texas based online vendor.<ref name="NY Daily news"> Breaking Bad: Digital Drug Sales, Analog Drug Deaths. Craig Malisow, Houston Press, March 13, 2013 | http://www.houstonpress.com/2013-03-14/news/motion-research-charles-carlton/</ref> | ||
A 21-year-old man from Little Rock, Arkansas died in October 2012 after taking a liquid drop of the | A 21-year-old man from Little Rock, Arkansas died in October 2012 after taking a liquid drop of the substance nasally at a music festival. He was reported to have consumed caffeinated alcoholic beverages for "several hours" beforehand. It is unclear what other drugs he may have consumed, as autopsies generally do not test for the presence of research chemicals.<ref name="21 yr old dies"> 21-year-old dies after one drop of new synthetic substance at Voodoo Fest. Naomi Martin, NOLA, November 1, 2012 | http://www.nola.com/crime/index.ssf/2012/11/21-year-old_dies_after_one_dro.html#incart_m-rpt-2/</ref> | ||
A man in Australia died from injuries sustained by running into trees and power poles while intoxicated by 25I-NBOMe.<ref name="Australia death"> New hallucinogenic | A man in Australia died from injuries sustained by running into trees and power poles while intoxicated by 25I-NBOMe.<ref name="Australia death"> New hallucinogenic substance 25B-NBOMe and 25I-NBOMe led to South Australian man's bizarre death | http://www.adelaidenow.com.au/news/south-australia/new-hallucinogenic-drug-25b-nbome-and-25i-nbome-led-to-south-australian-mans-bizarre-death/story-e6frea83-1226472672220/</ref> | ||
The addition of 5HTP can greatly increase the effects of 25i-NBOME and should be avoided.{{citation needed}} | The addition of 5HTP can greatly increase the effects of 25i-NBOME and should be avoided.{{citation needed}} | ||
It is strongly recommended that one use [[responsible | It is strongly recommended that one use [[responsible substance use|harm reduction practices]] when using this drug. | ||
===Tolerance and addiction potential=== | ===Tolerance and addiction potential=== | ||
25I-NBOMe is [[Addiction potential::not habit-forming]] and the desire to use it can actually decrease with use. It is most often self-regulating. | 25I-NBOMe is [[Addiction potential::not habit-forming]] and the desire to use it can actually decrease with use. It is most often self-regulating. | ||
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==Legal issues== | ==Legal issues== | ||
*'''Australia:''' Possession, production and sale is illegal. | *'''Australia:''' Possession, production and sale is illegal. | ||
*'''Israel:''' The | *'''Israel:''' The substance was banned in 2012.<ref>http://www.health.gov.il/LegislationLibrary/25574413.pdf</ref> | ||
*'''Russia:''' Possession, production and sale is illegal. | *'''Russia:''' Possession, production and sale is illegal. | ||
*'''Sweden:''' 25I-NBOMe is classed as Schedule I.<ref>Läkemedelsverkets författningssamling - http://www.lakemedelsverket.se/upload/lvfs/LVFS_2013-15.pdf</ref> | *'''Sweden:''' 25I-NBOMe is classed as Schedule I.<ref>Läkemedelsverkets författningssamling - http://www.lakemedelsverket.se/upload/lvfs/LVFS_2013-15.pdf</ref> | ||