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2C-H: Difference between revisions
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'''2C-H''' ('''2,5-Dimethoxyphenethylamine''') is a lesser-known [[substituted phenethylamine]] that is the traditional precursor to [[2C-B]], [[2C-C]] and [[2C-I]]. It was first synthesized in 1932 by Johannes S. Buck and was later studied in the 1970s by [[Alexander Shulgin]], who published his findings in his book [[PiHKAL]]. | '''2C-H''' ('''2,5-Dimethoxyphenethylamine''') is a lesser-known [[substituted phenethylamine]] that is the traditional precursor to [[2C-B]], [[2C-C]] and [[2C-I]]. It was first synthesized in 1932 by Johannes S. Buck and was later studied in the 1970s by [[Alexander Shulgin]], who published his findings in his book [[PiHKAL]]. | ||
Shulgin lists both the dosage and duration as unknown, as 2C-H is likely easily broken down by the MAO enzyme in the liver and is thus considered probably inactive. However, there are some anecdotal reports online suggesting that it may be active when taken [[sublingual]]ly.<ref>So Happy, Very Happy 2C-H by PandaDoom (Erowid) | https://erowid.org/experiences/exp.php?ID=80334</ref> When combined with | Shulgin lists both the dosage and duration as unknown, as 2C-H is likely easily broken down by the MAO enzyme in the liver and is thus considered probably inactive. However, there are some anecdotal reports online suggesting that it may be active when taken [[sublingual]]ly.<ref>So Happy, Very Happy 2C-H by PandaDoom (Erowid) | https://erowid.org/experiences/exp.php?ID=80334</ref> When combined with an [[MAOI]], it may be [[oral]]ly active. | ||
==Chemistry== | ==Chemistry== | ||
2C-H or 2,5-dimethoxyphenethylamine is a substituted [[phenethylamines|phenethylamine]] featuring a phenyl ring bound to an amino (NH<sub>2</sub>) group through an ethyl chain. 2C-H contains methoxy functional groups CH<sub>3</sub>O- attached to carbons R<sub>2</sub> and R<sub>5</sub> as well as a hydrogen atom attached to carbon R<sub>4</sub> of the phenyl ring. 2C-H belongs to the [[2C-x|2C]] family of phenethylamines which contain methoxy groups on the 2 and 5 positions of the benzene ring, and is also their simplest member. It is commonly used as a precursor to other compounds of the [[2C-x|2C family]], including [[2C-B]], [[2C-C]], [[2C-I]], and [[2C-N]]. | 2C-H, or 2,5-dimethoxyphenethylamine, is a substituted [[phenethylamines|phenethylamine]] featuring a phenyl ring bound to an amino (NH<sub>2</sub>) group through an ethyl chain. 2C-H contains methoxy functional groups CH<sub>3</sub>O- attached to carbons R<sub>2</sub> and R<sub>5</sub> as well as a hydrogen atom attached to carbon R<sub>4</sub> of the phenyl ring. 2C-H belongs to the [[2C-x|2C]] family of phenethylamines which contain methoxy groups on the 2 and 5 positions of the benzene ring, and is also their simplest member. It is commonly used as a precursor to other compounds of the [[2C-x|2C family]], including [[2C-B]], [[2C-C]], [[2C-I]], and [[2C-N]]. | ||
==Pharmacology== | ==Pharmacology== | ||
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==Toxicity and harm potential== | ==Toxicity and harm potential== | ||
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| [[File:Lolol.png|17px]]''Main articles: [[Research chemicals#Toxicity and harm potential|Research chemicals § Toxicity and harm potential]]'' ''&'' ''[[Responsible use #Hallucinogens|Responsible use § Hallucinogens]]'' | |||
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The toxicity and long-term health effects of recreational 2C-H use do not seem to have been studied in any scientific context and the exact [[Toxicity::toxic dose is unknown]]. This is because 2C-H is a [[research chemical]] with very little history of human usage. Independent research should always be done to ensure that a combination of two or more substances is safe before consumption. | The toxicity and long-term health effects of recreational 2C-H use do not seem to have been studied in any scientific context and the exact [[Toxicity::toxic dose is unknown]]. This is because 2C-H is a [[research chemical]] with very little history of human usage. Independent research should always be done to ensure that a combination of two or more substances is safe before consumption. | ||
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==References== | ==References== | ||
<references/> | <references/> | ||
[[Category:Phenethylamine]] | [[Category:Phenethylamine]][[Category:Psychoactive substance]][[Category:Psychoactive substances]][[Category:Substance]] | ||