Volumetric liquid dosing: Difference between revisions

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{{headerpanel|{{Disclaimer}} {{proofread}}}}

'''Volumetric dosing''' is the process of dissolving a compound in a liquid to make it easier to measure. In the interest of harm reduction, it is important to use volumetric dosing with certain compounds ~~which~~ are too potent to measure with traditional weighing scales. This technique makes it possible to use a cheap $30 scale and still measure accurately to ~~only~~ a few milligrams.<ref>Liquid Measurement Technique by Zam (Erowid) | https://www.erowid.org/psychoactives/dose/dose_info1.shtml</ref>

'''Volumetric dosing''' is the process of dissolving a compound in a liquid to make it easier to measure. In the interest of harm reduction, it is important to use volumetric dosing with certain compounds that are too potent to measure with traditional weighing scales. This technique makes it possible to use a cheap $30 scale and still measure accurately to a few milligrams.<ref>Liquid Measurement Technique by Zam (Erowid) | https://www.erowid.org/psychoactives/dose/dose_info1.shtml</ref>

Many psychoactive substances, including [[benzodiazepines]] and certain [[psychedelic]]s, are active at less than a single milligram. Such small quantities cannot be accurately measured with common digital scales, so the drug must instead be dosed volumetrically by weighing out larger amounts the compound and dissolving it in a calculated volume of a suitable liquid.

Many psychoactive substances, including [[benzodiazepines]] and certain [[psychedelic]]s, are active at less than a single milligram. Such small quantities cannot be accurately measured with common digital scales, so the drug must instead be dosed volumetrically by weighing out larger amounts of the compound and dissolving it in a calculated volume of a suitable liquid.

There is a volumetric dosing calculator located [http://volume.tripsit.me/ here] which will calculate the amount of drug and solvent needed as well as the concentration.

There is a volumetric dosing calculator located [http://volume.tripsit.me/ here] which will calculate the amount of drug and solvent needed, as well as the concentration.

==Materials==

*'''Solvent such as alcohol''' (vodka or everclear work best), '''water, [http://www.amazon.com/s/ref=nb_sb_noss_2?url=search-alias%3Daps&field-keywords=Propylene+glycol propylene glycol], or [http://www.amazon.com/s/ref=nb_sb_noss_2?url=search-alias%3Daps&field-keywords=glycerine&rh=i%3Aaps%2Ck%3Aglycerine glycerine]''' (depending on substance)

*'''Solvent, such as alcohol''' (vodka or everclear work best), '''water, [http://www.amazon.com/s/ref=nb_sb_noss_2?url=search-alias%3Daps&field-keywords=Propylene+glycol propylene glycol], or [http://www.amazon.com/s/ref=nb_sb_noss_2?url=search-alias%3Daps&field-keywords=glycerine&rh=i%3Aaps%2Ck%3Aglycerine glycerine]''' (depending on substance)

**Note: [http://www.google.com Search the internet] to determine what solvent to use. All drugs should dissolve in alcohol, but many drugs will not dissolve in water.

*'''Liquid measurement device''' such as a '''syringe''' (can be an oral syringe or one with a needle), '''graduated cylinder, eyedropper, measuring pipette, or measuring cups''' (teaspoon, tablespoon, etc)

*'''Liquid measurement device''', such as a '''syringe''' (can be an oral syringe or one with a needle), '''graduated cylinder, eyedropper, measuring pipette, or measuring cups''' (teaspoon, tablespoon, etc.)

*'''[[Dosage#Milligram scales|Milligram scale]]'''

*'''Sealed storage bottle or container'''

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==Solvent==

Certain psychoactive substances (particularly benzodiazepines) are practically insoluble in water, but will dissolve at various concentrations in other easy to acquire solvents such as alcohol, [http://www.amazon.com/s/ref=nb_sb_noss_2?url=search-alias%3Daps&field-keywords=Propylene+glycol propylene glycol], or [http://www.amazon.com/s/ref=nb_sb_noss_2?url=search-alias%3Daps&field-keywords=glycerine&rh=i%3Aaps%2Ck%3Aglycerine glycerine].

Certain psychoactive substances (particularly benzodiazepines) are practically insoluble in water, but will dissolve at various concentrations in other easy-to-acquire solvents, such as alcohol, [http://www.amazon.com/s/ref=nb_sb_noss_2?url=search-alias%3Daps&field-keywords=Propylene+glycol propylene glycol], or [http://www.amazon.com/s/ref=nb_sb_noss_2?url=search-alias%3Daps&field-keywords=glycerine&rh=i%3Aaps%2Ck%3Aglycerine glycerine].

The first important consideration is the maximum concentration at which your chosen solvent will dissolve your product. A value can usually be found with minimal effort on the internet, using a search term like "''<material> <solvent> solubility''".

~~Beneficially, alcohol~~ is mixable with most solvents. Just a few drops is usually enough to increase the maximum concentration dramatically, even when using water as the major component.

Alcohol in particular is mixable with most solvents; Just a few drops is usually enough to increase the maximum concentration dramatically, even when using water as the major component.

==Measurement==

There is a volumetric dosing calculator located [http://volume.tripsit.me/ here] which will calculate the amount of drug and solvent needed as well as the concentration.

There is a volumetric dosing calculator located [http://volume.tripsit.me/ here] which will calculate the amount of drug and solvent needed, as well as the concentration.

===Liquid===

[[File:OralSyringe2.jpg|250px|thumbnail|Oral syringes are ideal for measuring small amounts of liquid. They are commonly sold in pharmacies and are also available on [http://www.amazon.com/s/ref=nb_sb_noss_2?url=search-alias%3Dhpc&field-keywords=oral+syringe Amazon].]]

For best accuracy, an oral syringe should be used to measure the calculated volume of liquid. You may also use other measuring tools such as a syringe with a needle, graduated cylinder, eyedropper, measuring pipette, or measuring cups.

For best accuracy, an oral syringe should be used to measure the calculated volume of liquid. You may also use other measuring tools, such as a syringe with a needle, graduated cylinder, eyedropper, measuring pipette, or measuring cups.

The conversions for measuring cups are listed below:

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==Dissolution==

After weighing the material, calculating the concentration, and measuring the required volume of solvent~~; using~~ a suitable container ~~add the liquid~~ then carefully mix in the compound. Seal tightly ~~and~~ mix thoroughly by shaking the container vigorously.

After weighing the material, calculating the concentration, and measuring the required volume of solvent, add the liquid to a suitable container, then carefully mix in the compound. Seal tightly, then mix thoroughly by shaking the container vigorously.

To aid in dissolution, the container can be placed in a heat bath to warm it up. After a while the solvent will become less viscous and can be mixed more thoroughly.

To aid in dissolution, the container can be placed in a heat bath to warm it up. After a while, the solvent will become less viscous and can be mixed more thoroughly.

==Storage==

@@ Line 1: / Line 1: @@
 {{headerpanel|{{Disclaimer}} {{proofread}}}}
-'''Volumetric dosing''' is the process of dissolving a compound in a liquid to make it easier to measure. In the interest of harm reduction, it is important to use volumetric dosing with certain compounds which are too potent to measure with traditional weighing scales. This technique makes it possible to use a cheap $30 scale and still measure accurately to only a few milligrams.<ref>Liquid Measurement Technique by Zam (Erowid) | https://www.erowid.org/psychoactives/dose/dose_info1.shtml</ref>
+'''Volumetric dosing''' is the process of dissolving a compound in a liquid to make it easier to measure. In the interest of harm reduction, it is important to use volumetric dosing with certain compounds that are too potent to measure with traditional weighing scales. This technique makes it possible to use a cheap $30 scale and still measure accurately to a few milligrams.<ref>Liquid Measurement Technique by Zam (Erowid) | https://www.erowid.org/psychoactives/dose/dose_info1.shtml</ref>
-Many psychoactive substances, including [[benzodiazepines]] and certain [[psychedelic]]s, are active at less than a single milligram. Such small quantities cannot be accurately measured with common digital scales, so the drug must instead be dosed volumetrically by weighing out larger amounts the compound and dissolving it in a calculated volume of a suitable liquid.
+Many psychoactive substances, including [[benzodiazepines]] and certain [[psychedelic]]s, are active at less than a single milligram. Such small quantities cannot be accurately measured with common digital scales, so the drug must instead be dosed volumetrically by weighing out larger amounts of the compound and dissolving it in a calculated volume of a suitable liquid.
-There is a volumetric dosing calculator located [http://volume.tripsit.me/ here] which will calculate the amount of drug and solvent needed as well as the concentration.
+There is a volumetric dosing calculator located [http://volume.tripsit.me/ here] which will calculate the amount of drug and solvent needed, as well as the concentration.
 ==Materials==
-*'''Solvent such as alcohol''' (vodka or everclear work best), '''water, [http://www.amazon.com/s/ref=nb_sb_noss_2?url=search-alias%3Daps&field-keywords=Propylene+glycol propylene glycol], or [http://www.amazon.com/s/ref=nb_sb_noss_2?url=search-alias%3Daps&field-keywords=glycerine&rh=i%3Aaps%2Ck%3Aglycerine glycerine]''' (depending on substance)
+*'''Solvent, such as alcohol''' (vodka or everclear work best), '''water, [http://www.amazon.com/s/ref=nb_sb_noss_2?url=search-alias%3Daps&field-keywords=Propylene+glycol propylene glycol], or [http://www.amazon.com/s/ref=nb_sb_noss_2?url=search-alias%3Daps&field-keywords=glycerine&rh=i%3Aaps%2Ck%3Aglycerine glycerine]''' (depending on substance)
 **Note: [http://www.google.com Search the internet] to determine what solvent to use. All drugs should dissolve in alcohol, but many drugs will not dissolve in water.
-*'''Liquid measurement device''' such as a '''syringe''' (can be an oral syringe or one with a needle), '''graduated cylinder, eyedropper, measuring pipette, or measuring cups''' (teaspoon, tablespoon, etc)
+*'''Liquid measurement device''', such as a '''syringe''' (can be an oral syringe or one with a needle), '''graduated cylinder, eyedropper, measuring pipette, or measuring cups''' (teaspoon, tablespoon, etc.)
 *'''[[Dosage#Milligram scales|Milligram scale]]'''
 *'''Sealed storage bottle or container'''
@@ Line 15: / Line 15: @@
 ==Solvent==
-Certain psychoactive substances (particularly benzodiazepines) are practically insoluble in water, but will dissolve at various concentrations in other easy to acquire solvents such as alcohol, [http://www.amazon.com/s/ref=nb_sb_noss_2?url=search-alias%3Daps&field-keywords=Propylene+glycol propylene glycol], or [http://www.amazon.com/s/ref=nb_sb_noss_2?url=search-alias%3Daps&field-keywords=glycerine&rh=i%3Aaps%2Ck%3Aglycerine glycerine].
+Certain psychoactive substances (particularly benzodiazepines) are practically insoluble in water, but will dissolve at various concentrations in other easy-to-acquire solvents, such as alcohol, [http://www.amazon.com/s/ref=nb_sb_noss_2?url=search-alias%3Daps&field-keywords=Propylene+glycol propylene glycol], or [http://www.amazon.com/s/ref=nb_sb_noss_2?url=search-alias%3Daps&field-keywords=glycerine&rh=i%3Aaps%2Ck%3Aglycerine glycerine].
 The first important consideration is the maximum concentration at which your chosen solvent will dissolve your product. A value can usually be found with minimal effort on the internet, using a search term like "''<material> <solvent> solubility''".
-Beneficially, alcohol is mixable with most solvents. Just a few drops is usually enough to increase the maximum concentration dramatically, even when using water as the major component.
+Alcohol in particular is mixable with most solvents; Just a few drops is usually enough to increase the maximum concentration dramatically, even when using water as the major component.
 ==Measurement==
-There is a volumetric dosing calculator located [http://volume.tripsit.me/ here] which will calculate the amount of drug and solvent needed as well as the concentration.
+There is a volumetric dosing calculator located [http://volume.tripsit.me/ here] which will calculate the amount of drug and solvent needed, as well as the concentration.
 ===Liquid===
 [[File:OralSyringe2.jpg|250px|thumbnail|Oral syringes are ideal for measuring small amounts of liquid. They are commonly sold in pharmacies and are also available on [http://www.amazon.com/s/ref=nb_sb_noss_2?url=search-alias%3Dhpc&field-keywords=oral+syringe Amazon].]]
-For best accuracy, an oral syringe should be used to measure the calculated volume of liquid. You may also use other measuring tools such as a syringe with a needle, graduated cylinder, eyedropper, measuring pipette, or measuring cups.
+For best accuracy, an oral syringe should be used to measure the calculated volume of liquid. You may also use other measuring tools, such as a syringe with a needle, graduated cylinder, eyedropper, measuring pipette, or measuring cups.
 The conversions for measuring cups are listed below:
@@ Line 43: / Line 43: @@
 ==Dissolution==
-After weighing the material, calculating the concentration, and measuring the required volume of solvent; using a suitable container add the liquid then carefully mix in the compound. Seal tightly and mix thoroughly by shaking the container vigorously.
+After weighing the material, calculating the concentration, and measuring the required volume of solvent, add the liquid to a suitable container, then carefully mix in the compound. Seal tightly, then mix thoroughly by shaking the container vigorously.
-To aid in dissolution, the container can be placed in a heat bath to warm it up. After a while the solvent will become less viscous and can be mixed more thoroughly.
+To aid in dissolution, the container can be placed in a heat bath to warm it up. After a while, the solvent will become less viscous and can be mixed more thoroughly.
 ==Storage==