NEP: Difference between revisions

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| ''[[Ethyl-Pentedrone/Summary|Summary sheet: Ethyl-Pentedrone]]''

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'''Ethyl-pentedrone''' (also known as '''n-ethyl-pentedrone''' and '''NEP''') is a [[Stimulant|stimulant]] [[research chemical]] belonging to the [[~~Cathinone~~|cathinone]] ~~group~~. Ethyl-pentedrone's stimulation is believed to be caused by its affinity as an NDRI ([[norepinephrine]]-[[dopamine]] reuptake inhibitor); however, there have been no scientific studies confirming this. It may also act as a serotonin reuptake inhibitor or releasing agent in moderate to high doses, but this is only speculation.

'''Ethyl-pentedrone''' (also known as '''n-ethyl-pentedrone''' and '''NEP''') is a [[Stimulant|stimulant]] [[research chemical]] belonging to the [[Substituted cathinone|cathinone]] class. Ethyl-pentedrone's stimulation is believed to be caused by its affinity as an NDRI ([[norepinephrine]]-[[dopamine]] reuptake inhibitor); however, there have been no scientific studies confirming this. It may also act as a serotonin reuptake inhibitor or releasing agent in moderate to high doses, but this is only speculation.

Ethyl-pentedrone is closely related to [[pentedrone]], with an added ethyl-group on the carbon chain containing the nitrogen. This addition makes it about 3x as potent as pentedrone. Ethyl-pentedrone is also closely related to ethyl-hexedrone, and is likely very similar in effects.

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Ethyl-pentedrone first became known in the [[research chemical]] market during 2016. Little research exists about ethyl-pentedrone and its parent compound pentedrone. All dosage information found on the internet should be treated with caution.

==Chemistry==

Ethyl-pentedrone is a [[~~Cathinone~~|~~substituted~~ cathinone]], which means that it features a [[phenethylamine]] core with an alkyl group attached to the alpha carbon and an oxygen group attached to the beta carbon. Cathinones are beta-ketone analogues of [[amphetamine]]s.

Ethyl-pentedrone is a [[Substituted cathinone|cathinone]], which means that it features a [[phenethylamine]] core with an alkyl group attached to the alpha carbon and an oxygen group attached to the beta carbon. Cathinones are beta-ketone analogues of [[amphetamine]]s.

==Pharmacology==

Due to the lack of research regarding the substance, all discussion regarding the pharmacology of it is purely based upon its structure and subjective effect similarities to other [[cathinone]]s such as [[mephedrone]] and others. Ethyl-Pentedrone most likely acts as both a [[dopamine]] and [[norepinephrine]] [[releasing agent]] or [[reuptake inhibitor]]. This allows dopamine and norepinephrine to accumulate within the brain, resulting in [[stimulation|stimulating]] and [[physical euphoria|euphoric]] effects. It is possible that it may have some serotonergic properties, as users have described some entactogenic feelings.

Due to the lack of research regarding the substance, all discussion regarding the pharmacology of it is purely based upon its structure and subjective effect similarities to other [[Substituted cathinone|cathinone]]s such as [[mephedrone]] and others. Ethyl-Pentedrone most likely acts as both a [[dopamine]] and [[norepinephrine]] [[releasing agent]] or [[reuptake inhibitor]]. This allows dopamine and norepinephrine to accumulate within the brain, resulting in [[stimulation|stimulating]] and [[physical euphoria|euphoric]] effects. It is possible that it may have some serotonergic properties, as users have described some entactogenic feelings.

==Subjective effects==

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*[[Responsible use]]

*[[Stimulant]]

*[[Cathinone]]

*[[Substituted cathinone|Cathinone]]

==External links==

*[http://drugs.tripsit.me/ethyl-pentedrone Ethyl-Pentedrone (TripSit)]

@@ Line 6: / Line 6: @@
 | ''[[Ethyl-Pentedrone/Summary|Summary sheet: Ethyl-Pentedrone]]''
 |}
-'''Ethyl-pentedrone''' (also known as '''n-ethyl-pentedrone''' and '''NEP''') is a [[Stimulant|stimulant]] [[research chemical]] belonging to the [[Cathinone|cathinone]] group. Ethyl-pentedrone's stimulation is believed to be caused by its affinity as an NDRI ([[norepinephrine]]-[[dopamine]] reuptake inhibitor); however, there have been no scientific studies confirming this. It may also act as a serotonin reuptake inhibitor or releasing agent in moderate to high doses, but this is only speculation.
+'''Ethyl-pentedrone''' (also known as '''n-ethyl-pentedrone''' and '''NEP''') is a [[Stimulant|stimulant]] [[research chemical]] belonging to the [[Substituted cathinone|cathinone]] class. Ethyl-pentedrone's stimulation is believed to be caused by its affinity as an NDRI ([[norepinephrine]]-[[dopamine]] reuptake inhibitor); however, there have been no scientific studies confirming this. It may also act as a serotonin reuptake inhibitor or releasing agent in moderate to high doses, but this is only speculation.
 Ethyl-pentedrone is closely related to [[pentedrone]], with an added ethyl-group on the carbon chain containing the nitrogen. This addition makes it about 3x as potent as pentedrone. Ethyl-pentedrone is also closely related to ethyl-hexedrone, and is likely very similar in effects.
@@ Line 12: / Line 12: @@
 Ethyl-pentedrone first became known in the [[research chemical]] market during 2016. Little research exists about ethyl-pentedrone and its parent compound pentedrone. All dosage information found on the internet should be treated with caution.
 ==Chemistry==
-Ethyl-pentedrone is a [[Cathinone|substituted cathinone]], which means that it features a [[phenethylamine]] core with an alkyl group attached to the alpha carbon and an oxygen group attached to the beta carbon. Cathinones are beta-ketone analogues of [[amphetamine]]s.
+Ethyl-pentedrone is a [[Substituted cathinone|cathinone]], which means that it features a [[phenethylamine]] core with an alkyl group attached to the alpha carbon and an oxygen group attached to the beta carbon. Cathinones are beta-ketone analogues of [[amphetamine]]s.
 ==Pharmacology==
-Due to the lack of research regarding the substance, all discussion regarding the pharmacology of it is purely based upon its structure and subjective effect similarities to other [[cathinone]]s such as [[mephedrone]] and others. Ethyl-Pentedrone most likely acts as both a [[dopamine]] and [[norepinephrine]] [[releasing agent]] or [[reuptake inhibitor]]. This allows dopamine and norepinephrine to accumulate within the brain, resulting in [[stimulation|stimulating]] and [[physical euphoria|euphoric]] effects. It is possible that it may have some serotonergic properties, as users have described some entactogenic feelings.
+Due to the lack of research regarding the substance, all discussion regarding the pharmacology of it is purely based upon its structure and subjective effect similarities to other [[Substituted cathinone|cathinone]]s such as [[mephedrone]] and others. Ethyl-Pentedrone most likely acts as both a [[dopamine]] and [[norepinephrine]] [[releasing agent]] or [[reuptake inhibitor]]. This allows dopamine and norepinephrine to accumulate within the brain, resulting in [[stimulation|stimulating]] and [[physical euphoria|euphoric]] effects. It is possible that it may have some serotonergic properties, as users have described some entactogenic feelings.
 ==Subjective effects==
@@ Line 87: / Line 87: @@
 *[[Responsible use]]
 *[[Stimulant]]
-*[[Cathinone]]
+*[[Substituted cathinone|Cathinone]]
 ==External links==
 *[http://drugs.tripsit.me/ethyl-pentedrone Ethyl-Pentedrone (TripSit)]