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Hexedrone: Difference between revisions
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| ''[[Hexedrone/Summary|Summary sheet: Hexedrone]]'' | | ''[[Hexedrone/Summary|Summary sheet: Hexedrone]]'' | ||
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'''Hexedrone''' is a [[research chemical]] [[Stimulant|stimulant]] that falls within the [[ | '''Hexedrone''' is a [[research chemical]] [[Stimulant|stimulant]] that falls within the [[Substituted cathinone|cathinone]] category. Considering its effects and its structure being closely related to [[Pentedrone]], this too is likely to be an [[Norepinephrine]]-[[Dopamine]]-[[Reuptake inhibitor|reuptake-inhibitor]] (NDRI). However, these assumptions have not already been confirmed, due to insufficient research. | ||
Due to the lack of research along with only little experience-based information, the presented data might turn out to have some inaccuracies. This should especially be taken into consideration when interpreting the dosage information. | Due to the lack of research along with only little experience-based information, the presented data might turn out to have some inaccuracies. This should especially be taken into consideration when interpreting the dosage information. | ||
==Chemistry== | ==Chemistry== | ||
Hexedrone is a [[ | Hexedrone is a [[Substituted cathinone|cathinone]], which is closely related to [[Amphetamines|amphetamines]], but have a ß-substituted ketone group as well. Relative to regular cathinone, which can be found in the Khat plant, hexedrone consists of two added substitutions. At the R<sub>2</sub> position, a n-Butyl substitution forms a hexan chain. The second substitution is a Methyl group, that's attached to the amine (R<sub>4</sub>), thus forming N-Methyl. | ||
==Pharmacology== | ==Pharmacology== | ||
Due to the lack of research regarding the substance, all discussion regarding the pharmacology of it is purely based upon its structure and subjective effect similarities to other [[cathinone]]s such as [[Pentedrone|pentedrone]] and others. Hexedrone most likely acts as both a [[dopamine]] and [[norepinephrine]] [[reuptake inhibitor]]. This allows [[Dopamine|dopamine]] and [[Norepinephrine|norepinephrine]] to build up within the brain, resulting in [[stimulation|stimulating]] and [[physical euphoria|euphoric]] effects. | Due to the lack of research regarding the substance, all discussion regarding the pharmacology of it is purely based upon its structure and subjective effect similarities to other [[Substituted cathinone|cathinone]]s such as [[Pentedrone|pentedrone]] and others. Hexedrone most likely acts as both a [[dopamine]] and [[norepinephrine]] [[reuptake inhibitor]]. This allows [[Dopamine|dopamine]] and [[Norepinephrine|norepinephrine]] to build up within the brain, resulting in [[stimulation|stimulating]] and [[physical euphoria|euphoric]] effects. | ||
The decreased potency, compared to both pentedrone as well as [[Ethyl-Hexedrone|ethyl-hexedrone]] can be easily explained. Compared to pentedrone, there's a larger non-polar side chain. Ethyl-hexedrone has an ethyl group, instead of a methyl, which results in a significantly shifted electronegativity. | The decreased potency, compared to both pentedrone as well as [[Ethyl-Hexedrone|ethyl-hexedrone]] can be easily explained. Compared to pentedrone, there's a larger non-polar side chain. Ethyl-hexedrone has an ethyl group, instead of a methyl, which results in a significantly shifted electronegativity. | ||
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*[[Responsible use]] | *[[Responsible use]] | ||
*[[Stimulant]] | *[[Stimulant]] | ||
*[[Cathinone]] | *[[Substituted cathinone|Cathinone]] | ||
==External links== | ==External links== | ||
*[https://en.wikipedia.org/wiki/Hexedrone Hexedrone (Wikipedia)] | *[https://en.wikipedia.org/wiki/Hexedrone Hexedrone (Wikipedia)] | ||