Methoxetamine: Difference between revisions

Line 25:

Because of its structural similarity to [[3-OH-PCP]], MXE was falsely believed to carry [[opioid]] properties.<ref>Morris, H., & Wallach, J. (2014). From PCP to MXE: A comprehensive review of the non-medical use of dissociative drugs. Drug Testing and Analysis. https://doi.org/10.1002/dta.1620</ref> This claim cannot be supported by actual data, instead showing only insignificant affinity for the µ-opioid receptor by MXE itself, although in-vivo metabolites could yield different effects.<ref name="MXE Binding Profile"/>

<ref>https://www.gov.uk/government/uploads/system/uploads/attachment_data/file/119087/methoxetamine2012.pdf</ref> and a [[dopamine]] [[reuptake inhibitor]] with unsubstantiated claims of [[Opioid receptors|µ-opioid]] affinity and typical [[Dissociatives#Subjective effects|dissociative]] effects. This provides an explanation for its euphoric and often stimulating effects.

==Subjective effects==

@@ Line 25: / Line 25: @@
 Because of its structural similarity to [[3-OH-PCP]], MXE was falsely believed to carry [[opioid]] properties.<ref>Morris, H., & Wallach, J. (2014). From PCP to MXE: A comprehensive review of the non-medical use of dissociative drugs. Drug Testing and Analysis. https://doi.org/10.1002/dta.1620</ref> This claim cannot be supported by actual data, instead showing only insignificant affinity for the µ-opioid receptor by MXE itself, although in-vivo metabolites could yield different effects.<ref name="MXE Binding Profile"/>
-<ref>https://www.gov.uk/government/uploads/system/uploads/attachment_data/file/119087/methoxetamine2012.pdf</ref> and a [[dopamine]] [[reuptake inhibitor]] with unsubstantiated claims of [[Opioid receptors|µ-opioid]] affinity and typical [[Dissociatives#Subjective effects|dissociative]] effects. This provides an explanation for its euphoric and often stimulating effects.
 ==Subjective effects==