Pethidine: Difference between revisions

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One of pethdine's metabolites, norpethidine has little to no opioid action, but is know to cause seizures. Pethidine should not be taken during [[Benzodiazepine#Discontinuation|benzodiazepine withdrawals]] as this can potentially cause [[seizure]]s. In 1984, Libby Zion, a teenager was brought to the emergency room due to a "flu-like" ailment. She was previously prescribed and taking phenelzine, a [[MAOI |monoamine oxidase inhibitor]], which in combination caused fatal serotonin syndrome.<ref> Serotonin Syndrome and the Libby Zion Affair | http://epmonthly.com/article/serotonin-syndrome-and-the-libby-zion-affair/ </ref>

It is strongly recommended that one use [[responsible drug use|harm reduction practices]] when using this drug.

Revision as of 17:12, 20 November 2016 view source >Sir Kibs →Toxicity and harm potential ← Older edit		Revision as of 09:38, 29 November 2016 view source >Oskykins →Toxicity and harm potential Newer edit →
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	One of pethdine's metabolites, norpethidine has little to no opioid action, but is know to cause seizures. Pethidine should not be taken during [[Benzodiazepine#Discontinuation\|benzodiazepine withdrawals]] as this can potentially cause [[seizure]]s. In 1984, Libby Zion, a teenager was brought to the emergency room due to a "flu-like" ailment. She was previously prescribed and taking phenelzine, a [[MAOI \|monoamine oxidase inhibitor]], which in combination caused fatal serotonin syndrome.<ref> Serotonin Syndrome and the Libby Zion Affair \| http://epmonthly.com/article/serotonin-syndrome-and-the-libby-zion-affair/ </ref>		One of pethdine's metabolites, norpethidine has little to no opioid action, but is know to cause seizures. Pethidine should not be taken during [[Benzodiazepine#Discontinuation\|benzodiazepine withdrawals]] as this can potentially cause [[seizure]]s. In 1984, Libby Zion, a teenager was brought to the emergency room due to a "flu-like" ailment. She was previously prescribed and taking phenelzine, a [[MAOI \|monoamine oxidase inhibitor]], which in combination caused fatal serotonin syndrome.<ref> Serotonin Syndrome and the Libby Zion Affair \| http://epmonthly.com/article/serotonin-syndrome-and-the-libby-zion-affair/ </ref>


	It is strongly recommended that one use [[responsible drug use\|harm reduction practices]] when using this drug.		It is strongly recommended that one use [[responsible drug use\|harm reduction practices]] when using this drug.