This is an unofficial archive of PsychonautWiki as of 2025-08-11T15:14:44Z. Content on this page may be outdated, incomplete, or inaccurate. Please refer to the original page for the most up-to-date information.
Harmala alkaloid: Difference between revisions
>Oskykins |
>Oskykins |
||
| Line 2: | Line 2: | ||
==Chemistry== | ==Chemistry== | ||
Harmala alkaloids are substituted derivatives of the molecule [[beta-Carbolines|''beta''-carboline]]. The structure of''beta''-carboline is comprised of an indole skeleton fused to a pyridine ring. Harmine, harmaline, and tetrahydroharmaline share structural subsitutions | Harmala alkaloids are substituted derivatives of the molecule [[beta-Carbolines|''beta''-carboline]]. The structure of''beta''-carboline is comprised of an indole skeleton fused to a pyridine ring. Harmine, harmaline, and tetrahydroharmaline share structural subsitutions and they all contain a methoxy group at R<sub>7</sub> and a methyl group at R<sub>1</sub>. They differ in the saturation of their six-member nitrogenous ring. Harmine contains an unsaturated pyridine ring while harmaline contains a dihydrogenated pyridine ring. Tetrahydroharmaline is saturated with four additional hydrogen bonds than harmine. | ||
==Pharmacology== | ==Pharmacology== | ||