5-Hydroxytryptophan: Difference between revisions
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===Physical effects=== | ===Physical effects=== | ||
For some individuals, 5-HTP can | For some individuals, 5-HTP can cause the following side effects (although rare). | ||
*'''[[Heartburn]]''' | *'''[[Heartburn]]''' | ||
*'''[[Stomach bloating]]''' | *'''[[Stomach bloating]]''' | ||
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*'''[[Nausea]] and vomiting''' | *'''[[Nausea]] and vomiting''' | ||
*'''[[Diarrhea]] | *'''[[Diarrhea]] | ||
==Toxicity and harm potential== | ==Toxicity and harm potential== | ||
Due to the conversion of 5-HTP into serotonin by the liver, there may be a significant risk of heart valve disease from serotonin's effect on the heart.<ref>https://www.ncbi.nlm.nih.gov/pubmed/15781732 | Long-term serotonin administration induces heart valve disease in rats.</ref><ref>https://www.ncbi.nlm.nih.gov/pubmed/12466135 | Serotonin mechanisms in heart valve disease II: the 5-HT2 receptor and its signaling pathway in aortic valve interstitial cells.</ref> | Due to the conversion of 5-HTP into serotonin by the liver, there may be a significant risk of heart valve disease from serotonin's effect on the heart.<ref>https://www.ncbi.nlm.nih.gov/pubmed/15781732 | Long-term serotonin administration induces heart valve disease in rats.</ref><ref>https://www.ncbi.nlm.nih.gov/pubmed/12466135 | Serotonin mechanisms in heart valve disease II: the 5-HT2 receptor and its signaling pathway in aortic valve interstitial cells.</ref> |