DOM: Difference between revisions

DOM is a selective [[5-HT2A receptor|5-HT_2A]], [[5-HT2B receptor|5-HT_2B]], and [[5-HT2C receptor|5-HT_2C receptor]] [[partial agonist]]. Its psychedelic effects are mediated by its [[agonist]]ic properties at the 5-HT_2A receptor. Due to its selectivity, DOM is often used in scientific research when studying the [[5-HT2|5-HT₂ receptor]] subfamily.  DOM is a [[Chirality (chemistry)|chiral]] molecule, and ''R''-(-)-DOM is the more active [[enantiomer]], functioning as a potent agonist of the serotonin [[5-HT]] family of receptors; mainly of the [[5-HT2]] subtype.<ref>Sanders-Bush, Burris, KD; Knoth, K, (September 1988). "Lysergic acid diethylamide and 2,5-dimethoxy-4-methylamphetamine are partial agonists at serotonin receptors linked to phosphoinositide hydrolysis" Journal of Pharmacology and Experimental Therapeutics '''246''' 3 924–928</ref>