5-APB: Difference between revisions

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| ''[[ 5-APB/Summary|Summary sheet: 5-APB]]''

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'''5-APB''' (also known as ~~'''5-(2-aminopropyl)benzofuran''',~~ '''1-~~benzofuran~~-5-ylpropan-2-amine''', or '''benzofury''') is a [[psychoactive class::stimulant]] and [[Psychoactive class::entactogen]]ic drug of the [[chemical class::phenethylamine]] and [[chemical class::benzofuran]] class.

'''5-APB''' (also known as '''1-Benzofuran-5-ylpropan-2-amine''', or '''benzofury''') is a [[psychoactive class::stimulant]] and [[Psychoactive class::entactogen]]ic drug of the [[chemical class::phenethylamine]] and [[chemical class::benzofuran]] class.

This compound is known for its [[stimulating]] and [[euphoria|euphoric]] effects which has resulted in its rise in popularity as a product which is easily accessible through the use of certain online [[research chemical]] vendors. It has been sold as a [[designer drug]] since 2010.<ref>EMCDDA–Europol 2010 Annual Report on the implementation of Council Decision 2005/387/JHA | http://www.emcdda.europa.eu/publications/implementation-reports/2010</ref>

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5-APB is commonly found as the succinate and hydrochloride salt. The hydrochloride salt is 10% more potent by mass so doses should be adjusted accordingly.

==Chemistry==

5-APB is a benzofuran and phenethylamine, so it has an ethylamine chain and a furan ring attached to the main benzene ring. It can also be classified as an amphetamine derivative because the ethylamine chain is alpha methylated. Molecules of the amphetamine class contain a [[phenethylamine]] core featuring a phenyl ring bound to an amino (NH2) group through an ethyl chain with an additional methyl substitution at R<sub>α</sub>. The oxygen in the furan ring is placed at the 5 position, which generally constitutes more stimulating effects than when the oxygen is placed at the 6 position, which is usually described as being more [[psychedelic]] in effects.

5-APB is a [[benzofuran]] and [[phenethylamine]], so it has an ethylamine chain and a furan ring attached to the main benzene ring. It can also be classified as an amphetamine derivative because the ethylamine chain is alpha methylated. Molecules of the amphetamine class contain a phenethylamine core featuring a phenyl ring bound to an amino (NH2) group through an ethyl chain with an additional methyl substitution at R<sub>α</sub>. The oxygen in the furan ring is placed at the 5 position, which generally constitutes more stimulating effects than when the oxygen is placed at the 6 position, which is usually described as being more [[psychedelic]] in effects.

==Pharmacology==

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 | ''[[ 5-APB/Summary|Summary sheet:  5-APB]]''
 |}
-'''5-APB''' (also known as '''5-(2-aminopropyl)benzofuran''', '''1-benzofuran-5-ylpropan-2-amine''', or '''benzofury''') is a [[psychoactive class::stimulant]] and [[Psychoactive class::entactogen]]ic drug of the [[chemical class::phenethylamine]] and [[chemical class::benzofuran]] class.
+'''5-APB''' (also known as '''1-Benzofuran-5-ylpropan-2-amine''', or '''benzofury''') is a [[psychoactive class::stimulant]] and [[Psychoactive class::entactogen]]ic drug of the [[chemical class::phenethylamine]] and [[chemical class::benzofuran]] class.
 This compound is known for its [[stimulating]] and [[euphoria|euphoric]] effects which has resulted in its rise in popularity as a product which is easily accessible through the use of certain online [[research chemical]] vendors. It has been sold as a [[designer drug]] since 2010.<ref>EMCDDA–Europol 2010 Annual Report on the implementation of Council Decision 2005/387/JHA | http://www.emcdda.europa.eu/publications/implementation-reports/2010</ref>
@@ Line 11: / Line 11: @@
 -APB is commonly found as the succinate and hydrochloride salt. The hydrochloride salt is 10% more potent by mass so doses should be adjusted accordingly.
 ==Chemistry==
--APB is a benzofuran and phenethylamine, so it has an ethylamine chain and a furan ring attached to the main benzene ring. It can also be classified as an amphetamine derivative because the ethylamine chain is alpha methylated. Molecules of the amphetamine class contain a [[phenethylamine]] core featuring a phenyl ring bound to an amino (NH2) group through an ethyl chain with an additional methyl substitution at R<sub>α</sub>. The oxygen in the furan ring is placed at the 5 position, which generally constitutes more stimulating effects than when the oxygen is placed at the 6 position, which is usually described as being more [[psychedelic]] in effects.
+-APB is a [[benzofuran]] and [[phenethylamine]], so it has an ethylamine chain and a furan ring attached to the main benzene ring. It can also be classified as an amphetamine derivative because the ethylamine chain is alpha methylated. Molecules of the amphetamine class contain a phenethylamine core featuring a phenyl ring bound to an amino (NH2) group through an ethyl chain with an additional methyl substitution at R<sub>α</sub>. The oxygen in the furan ring is placed at the 5 position, which generally constitutes more stimulating effects than when the oxygen is placed at the 6 position, which is usually described as being more [[psychedelic]] in effects.
 ==Pharmacology==