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Sleep-wake cycle: Difference between revisions
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*As adenosine is metabolized and it's levels decrease it no longer leads to the [[GABAergic]] inhibition of histamine, allowing vigilance to increase.<ref>http://www.ncbi.nlm.nih.gov/pubmed/21401496 | The role of adenosine in the regulation of sleep.</ref><ref>http://www.ncbi.nlm.nih.gov/pubmed/15748171 | An adenosine A receptor agonist induces sleep by increasing GABA release in the tuberomammillary nucleus to inhibit histaminergic systems in rats.</ref> | *As adenosine is metabolized and it's levels decrease it no longer leads to the [[GABAergic]] inhibition of histamine, allowing vigilance to increase.<ref>http://www.ncbi.nlm.nih.gov/pubmed/21401496 | The role of adenosine in the regulation of sleep.</ref><ref>http://www.ncbi.nlm.nih.gov/pubmed/15748171 | An adenosine A receptor agonist induces sleep by increasing GABA release in the tuberomammillary nucleus to inhibit histaminergic systems in rats.</ref> | ||
*As these elements of wakefulness begin to return [[REM cycles]] and brief awakenings occur with increasing density, eventually resulting in a full awakening. | *As these elements of wakefulness begin to return [[REM cycles]] and brief awakenings occur with increasing density, eventually resulting in a full awakening.<ref>https://en.wikipedia.org/wiki/Rapid_eye_movement_sleep#/media/File:Sleep_Hypnogram.svg | Hypnogram of sleep between midnight and 6.30 am</ref> | ||
==See also== | ==See also== | ||