This is an unofficial archive of PsychonautWiki as of 2025-08-11T15:14:44Z. Content on this page may be outdated, incomplete, or inaccurate. Please refer to the original page for the most up-to-date information.
Sleep-wake cycle: Difference between revisions
>CyborGhost |
>CyborGhost |
||
| Line 12: | Line 12: | ||
===After waking=== | ===After waking=== | ||
*Lack of Adenosine activating the (A(2A)R) receptor is sufficient to have decreased GABA release in the tuberomammillary nucleus enough to have enabled histamine wake one up and cause vigilance.<ref>http://www.ncbi.nlm.nih.gov/pubmed/15748171 | An adenosine A receptor agonist induces sleep by increasing GABA release in the tuberomammillary nucleus to inhibit histaminergic systems in rats.</ref><ref>http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3016451/ | HISTAMINE IN THE REGULATION OF WAKEFULNESS</ref> | *Lack of Adenosine activating the (A(2A)R) receptor is sufficient to have decreased GABA release in the tuberomammillary nucleus enough to have enabled histamine to wake one up and cause vigilance.<ref>http://www.ncbi.nlm.nih.gov/pubmed/15748171 | An adenosine A receptor agonist induces sleep by increasing GABA release in the tuberomammillary nucleus to inhibit histaminergic systems in rats.</ref><ref>http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3016451/ | HISTAMINE IN THE REGULATION OF WAKEFULNESS</ref> | ||
*Exposure to blue light frequencies mainly between 460 and 480nm<ref>https://www.ncbi.nlm.nih.gov/pubmed/11487664 | Action spectrum for melatonin regulation in humans: evidence for a novel circadian photoreceptor.</ref> trigger [[melanopsin]] cells in the eyes to send a signal to the suprachiasmatic nucleus<ref>http://www.nature.com/nrn/journal/v12/n10/fig_tab/nrn3086_F2.html | How light regulates the molecular clockwork in SCN neurons.</ref> which sends [[GABA]] to the [[pineal gland]], inhibiting it from releasing melatonin thereby causing levels to decline.<ref>https://www.researchgate.net/publication/241849993_GABA_release_from_SCN_terminals_is_necessary_for_the_light-induced_inhibition_of_nocturnal_melatonin_release_in_the_rat | GABA release from SCN terminals is necessary for the light-induced inhibition of nocturnal melatonin release in the rat</ref> | *Exposure to blue light frequencies mainly between 460 and 480nm<ref>https://www.ncbi.nlm.nih.gov/pubmed/11487664 | Action spectrum for melatonin regulation in humans: evidence for a novel circadian photoreceptor.</ref> trigger [[melanopsin]] cells in the eyes to send a signal to the suprachiasmatic nucleus<ref>http://www.nature.com/nrn/journal/v12/n10/fig_tab/nrn3086_F2.html | How light regulates the molecular clockwork in SCN neurons.</ref> which sends [[GABA]] to the [[pineal gland]], inhibiting it from releasing melatonin thereby causing levels to decline.<ref>https://www.researchgate.net/publication/241849993_GABA_release_from_SCN_terminals_is_necessary_for_the_light-induced_inhibition_of_nocturnal_melatonin_release_in_the_rat | GABA release from SCN terminals is necessary for the light-induced inhibition of nocturnal melatonin release in the rat</ref> | ||