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Sleep-wake cycle: Difference between revisions
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*Lack of Adenosine activating the (A(2A)R) receptor is | *Lack of Adenosine activating the (A(2A)R) receptor is sufficient to have decreased GABA release in the tuberomammillary nucleus enough to have enabled histamine wake one up and cause vigilance.<ref>http://www.ncbi.nlm.nih.gov/pubmed/15748171 | An adenosine A receptor agonist induces sleep by increasing GABA release in the tuberomammillary nucleus to inhibit histaminergic systems in rats.</ref> | ||
*Exposure to blue light frequencies mainly between 460 and 480nm trigger [[melanopsin]] cells in the eyes to send a signal to the suprachiasmatic nucleus (SCN) which sends [[GABA]] to the [[pineal gland]], inhibiting it from releasing melatonin thereby causing levels to decline. | *Exposure to blue light frequencies mainly between 460 and 480nm trigger [[melanopsin]] cells in the eyes to send a signal to the suprachiasmatic nucleus (SCN) which sends [[GABA]] to the [[pineal gland]], inhibiting it from releasing melatonin thereby causing levels to decline. | ||