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Harmala alkaloid: Difference between revisions
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Since [[DMT]] is broken down by monoamine oxidase A, inhibition of this enzyme allows for the oral activation of DMT and prolongs the experience for the duration of the harmala alkaloid effects. In combination, harmala alkaloids and DMT are known as [[ayahuasca]]. | Since [[DMT]] is broken down by monoamine oxidase A, inhibition of this enzyme allows for the oral activation of DMT and prolongs the experience for the duration of the harmala alkaloid effects. In combination, harmala alkaloids and DMT are known as [[ayahuasca]]. | ||
Harmala alkaloids, along with other beta-carbolines, also function as GABA-A receptor (benzodiazepine site) inverse agonists, likely contributing to their anxiogenic and convulsant effects.<ref>From the behavioral pharmacology of beta-carbolines to seizures, anxiety, and memory. | https://www.ncbi.nlm.nih.gov/pubmed/17334612</ref> | Harmala alkaloids, along with other beta-carbolines, also function as GABA-A receptor (benzodiazepine site) inverse agonists, likely contributing to their [[anxiety|anxiogenic]] and convulsant effects.<ref>From the behavioral pharmacology of beta-carbolines to seizures, anxiety, and memory. | https://www.ncbi.nlm.nih.gov/pubmed/17334612</ref> | ||
==Examples== | ==Examples== | ||