Reuptake inhibitor: Difference between revisions

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Neurotransmission occurs by transporting information across neurons by an electrical impulse called an action potential. When an action potential reaches the synapse between two neurons, the pre-synaptic neuron releases neurotransmitters to transport the chemical signal across the synapse by binding to receptors on the post-synaptic neuron. Reuptake is a required aspect of neurological activity which regulates the amount of neurotransmitter present in a synapse after the transmission of a neural signal.

Reuptake is a required function of activity in which a neurotransmitter is reabsorbed by a neurotransmitter transporter of a pre-synaptic neuron after it has performed its function of transmitting a neural impulse. Reuptake regulates the amount of neurotransmitter present in the synapse between neurons. Re-uptake, the process of removing transmitters after release, determines the extent, duration, and spatial domain of receptor activation.

Reuptake is necessary for normal synaptic physiology because it allows for the recycling of neurotransmitters and regulates the level of neurotransmitter present in the synapse, thereby controlling how long a signal resulting from neurotransmitter release lasts.

A '''reuptake inhibitor''', also known as a transporter blocker, is a drug that inhibits the reuptake of a [[neurotransmitter]] from the synapse into the presynaptic neurone, leading to an increase in the extracellular concentrations of the neurotransmitter and therefore an increase in neurotransmission. Various drugs utilize reuptake inhibition to exert their psychological and physiological effects, including many [[antidepressants]] and [[stimulants]].

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+Neurotransmission occurs by transporting information across neurons by an electrical impulse called an action potential. When an action potential reaches the synapse between two neurons, the pre-synaptic neuron releases neurotransmitters to transport the chemical signal across the synapse by binding to receptors on the post-synaptic neuron. Reuptake is a required aspect of neurological activity which regulates the amount of neurotransmitter present in a synapse after the transmission of a neural signal.
+Reuptake is a required function of  activity in which a neurotransmitter is reabsorbed by a neurotransmitter transporter of a pre-synaptic neuron after it has performed its function of transmitting a neural impulse. Reuptake regulates the amount of neurotransmitter present in the synapse between neurons. Re-uptake, the process of removing transmitters after release, determines the extent, duration, and spatial domain of receptor activation.
+Reuptake is necessary for normal synaptic physiology because it allows for the recycling of neurotransmitters and regulates the level of neurotransmitter present in the synapse, thereby controlling how long a signal resulting from neurotransmitter release lasts.
 A '''reuptake inhibitor''', also known as a transporter blocker, is a drug that inhibits the reuptake of a [[neurotransmitter]] from the synapse into the presynaptic neurone, leading to an increase in the extracellular concentrations of the neurotransmitter and therefore an increase in neurotransmission. Various drugs utilize reuptake inhibition to exert their psychological and physiological effects, including many [[antidepressants]] and [[stimulants]].