5F-PB-22: Difference between revisions

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==Toxicity and harm potential==

The toxicity and long-term health effects of recreational 5F-PB-22 use do not seem to have been studied in any scientific context and the [[Toxicity::exact toxic dosage is unknown]]. This is because 5F-PB-22 has very little history of human usage. Anecdotal evidence from people who have tried 5F-PB-22 within the community suggest that there do not seem to be any negative health effects attributed to simply trying this drug at low to moderate doses by itself and using it sparingly (but nothing can be completely guaranteed). Informal experiments have shown that overdose will cause physical discomfort including heart palpitations, vertigo and sedation at much lower than dangerous doses, usually causing the user to suffer large amounts of [[anxiety]] or to fall asleep.

The toxicity and long-term health effects of recreational 5F-PB-22 use do not seem to have been studied in any scientific context and the [[Toxicity::exact toxic dosage is unknown]]. This is because 5F-PB-22 has very little history of human usage. Informal experiments have shown that overdose will cause physical discomfort including heart palpitations, vertigo and sedation at much lower than dangerous doses, usually causing the user to suffer large amounts of [[anxiety]] or to fall asleep.

There have been many hospital reports involving 5F-PB-22, as well as ~~at least 4~~ cases of post-mortem analysis involving 5F-PB-22.<ref>jat.oxfordjournals.org/content/early/2014/05/29/jat.bku048.short</ref>

There have been many hospital reports involving 5F-PB-22, as well as cases of post-mortem analysis involving 5F-PB-22.<ref>jat.oxfordjournals.org/content/early/2014/05/29/jat.bku048.short</ref> Five deaths have been associated with the use of [[5F-PB-22]] in the United States.<ref>Perspectives of drugs: synthetic cannabinoids in Europe (European Monitoring Centre for Drugs and Drug Addiction | http://www.emcdda.europa.eu/topics/pods/synthetic-cannabinoids</ref>

It has often been recommended that those with severe pre-existing mental conditions should not ingest these substances due to the way they strongly increase [[emotion enhancement|one's current state of mind and emotions]]. Also, like [[THC]], prolonged usage of synthetic [[cannabinoids]] may increase one's disposition to mental illness and psychosis<ref>http://bjp.rcpsych.org/content/184/2/110.short</ref>, particularly in vulnerable individuals with risk factors for psychotic illnesses (like a past or family history of schizophrenia).<ref>Every-Palmer, S. [[Synthetic cannabinoid]] use and psychosis: an explorative study. Journal of Drug and Alcohol Dependence 2011.</ref><ref>http://www.sciencedirect.com/science/article/pii/S0736467910008802</ref><ref>http://journals.lww.com/pec-online/Abstract/2010/06000/A_Teenager_With_Agitation__Higher_Than_She_Should.16.aspx</ref>

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 ==Toxicity and harm potential==
 {{Main|Research chemicals#Toxicity and harm potential}}
-The toxicity and long-term health effects of recreational 5F-PB-22 use do not seem to have been studied in any scientific context and the [[Toxicity::exact toxic dosage is unknown]]. This is because 5F-PB-22 has very little history of human usage. Anecdotal evidence from people who have tried 5F-PB-22 within the community suggest that there do not seem to be any negative health effects attributed to simply trying this drug at low to moderate doses by itself and using it sparingly (but nothing can be completely guaranteed). Informal experiments have shown that overdose will cause physical discomfort including heart palpitations, vertigo and sedation at much lower than dangerous doses, usually causing the user to suffer large amounts of [[anxiety]] or to fall asleep.
+The toxicity and long-term health effects of recreational 5F-PB-22 use do not seem to have been studied in any scientific context and the [[Toxicity::exact toxic dosage is unknown]]. This is because 5F-PB-22 has very little history of human usage. Informal experiments have shown that overdose will cause physical discomfort including heart palpitations, vertigo and sedation at much lower than dangerous doses, usually causing the user to suffer large amounts of [[anxiety]] or to fall asleep.
-There have been many hospital reports involving 5F-PB-22, as well as at least 4 cases of post-mortem analysis involving 5F-PB-22.<ref>jat.oxfordjournals.org/content/early/2014/05/29/jat.bku048.short</ref>
+There have been many hospital reports involving 5F-PB-22, as well as cases of post-mortem analysis involving 5F-PB-22.<ref>jat.oxfordjournals.org/content/early/2014/05/29/jat.bku048.short</ref> Five deaths have been associated with the use of [[5F-PB-22]] in the United States.<ref>Perspectives of drugs: synthetic cannabinoids in Europe (European Monitoring Centre for Drugs and Drug Addiction | http://www.emcdda.europa.eu/topics/pods/synthetic-cannabinoids</ref>
 It has often been recommended that those with severe pre-existing mental conditions should not ingest these substances due to the way they strongly increase [[emotion enhancement|one's current state of mind and emotions]]. Also, like [[THC]], prolonged usage of synthetic [[cannabinoids]] may increase one's disposition to mental illness and psychosis<ref>http://bjp.rcpsych.org/content/184/2/110.short</ref>, particularly in vulnerable individuals with risk factors for psychotic illnesses (like a past or family history of schizophrenia).<ref>Every-Palmer, S. [[Synthetic cannabinoid]] use and psychosis: an explorative study. Journal of Drug and Alcohol Dependence 2011.</ref><ref>http://www.sciencedirect.com/science/article/pii/S0736467910008802</ref><ref>http://journals.lww.com/pec-online/Abstract/2010/06000/A_Teenager_With_Agitation__Higher_Than_She_Should.16.aspx</ref>