5-APB: Difference between revisions

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==Pharmacology==

~~{| class="wikitable"~~

|-

~~! Neurotransmitters !! Ki values~~

|-

~~| [[Norepinephrine]] || 180~~

|-

~~| [[Dopamine]] || 265~~

|-

~~| [[Serotonin]] || 811~~

|}

5-APB is a triple [[reuptake inhibitor]] for [[norepinephrine]], [[dopamine]] and [[serotonin]], as well as being an [[agonist]] for the [[Serotonin#The_5-HT_system|5-HT2A]] and [[Serotonin#The_5-HT_system|5-HT2B]] [[receptor]]s.<ref>The effects of benzofury (5-APB) on the dopamine transporter and 5-HT2-dependent vasoconstriction in the rat | https://www.ncbi.nlm.nih.gov/pubmed/24012617?dopt=Abstract</ref><ref>Neurochemical profiles of some novel psychoactive substances | http://www.sciencedirect.com/science/article/pii/S0014299912010114</ref> It has also been speculated that 5-APB is a [[monoamine]] [[releasing agent]].

@@ Line 9: / Line 9: @@
 ==Pharmacology==
-{| class="wikitable"
-|-
-! Neurotransmitters !! K<sub>i</sub> values
-|-
-| [[Norepinephrine]] || 180
-|-
-| [[Dopamine]] || 265
-|-
-| [[Serotonin]] || 811
-|}
 -APB is a triple [[reuptake inhibitor]] for [[norepinephrine]], [[dopamine]] and [[serotonin]], as well as being an [[agonist]] for the [[Serotonin#The_5-HT_system|5-HT<sub>2A</sub>]] and [[Serotonin#The_5-HT_system|5-HT<sub>2B</sub>]] [[receptor]]s.<ref>The effects of benzofury (5-APB) on the dopamine transporter and 5-HT2-dependent vasoconstriction in the rat | https://www.ncbi.nlm.nih.gov/pubmed/24012617?dopt=Abstract</ref><ref>Neurochemical profiles of some novel psychoactive substances | http://www.sciencedirect.com/science/article/pii/S0014299912010114</ref> It has also been speculated that 5-APB is a [[monoamine]] [[releasing agent]].