LSA adducts: Difference between revisions

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It has been documented that ~~'''Lysergic Acid Amide'''~~ (LSA) is capable of forming adducts with various aldehydes. <ref>http://www.nature.com/nature/journal/v192/n4802/abs/192552a0.html</ref> Such adducts can form spontaneously during extraction of LSA if aldehydes are introduced to the solution, and can alter the subjective and physiological effects of LSA. <ref>http://herbpedia.wikidot.com/</ref>

It has been documented that lysergic acid amide (LSA) is capable of forming adducts with various aldehydes.<ref>http://www.nature.com/nature/journal/v192/n4802/abs/192552a0.html</ref> Such adducts can form spontaneously during the extraction of LSA if aldehydes are introduced to the solution and can alter the subjective and physiological effects of LSA.<ref>http://herbpedia.wikidot.com/</ref>

==Lysergic ~~Acid Hydroxyethylamide~~==

==Lysergic acid hydroxyethylamide==

~~'''~~Lysergic ~~Acid Hydroxyethylamide'''~~ (LSH) is one example of such adducts, produced from LSA and acetaldehyde.

Lysergic acid hydroxyethylamide (LSH) is one example of such adducts, which is produced from LSA and acetaldehyde.

Due to the low boiling point of acetaldehyde (20.2 °C), LSH is very unstable and readily decomposes back into LSA and acetaldehyde. LSH and possibly other adducts are formed naturally in LSA containing plants, possibly explaining the differences in reported effects, as fresh seeds may contain higher levels of LSH.

Due to the low boiling point of acetaldehyde (20.2 °C), LSH is very unstable and readily decomposes back into LSA and acetaldehyde. LSH and possibly other adducts are formed naturally in LSA containing plants, possibly explaining the differences in reported effects as fresh seeds may contain higher levels of LSH.

LSA is possibly not the main active principal of Ipomea seeds as commonly thought, and appears instead to be a decomposition product of lysergic acid hydroxyethylamide (LSH). LSH is reported to have psychedelic properties similar to that of ~~'''Lysergic Acid Diethylamide'''~~ (LSD). Animal tests have shown that LSH produces stimulant effects similar to LSD, while LSA produces sedation. LSH is said to produce less vasoconstriction than LSA.

LSA is possibly not the main active principal of Ipomea seeds as commonly thought and appears instead to be a decomposition product of lysergic acid hydroxyethylamide (LSH). LSH is reported to have psychedelic properties similar to that of lysergic acid diethylamide (LSD). Animal tests have shown that LSH produces [[stimulation|stimulant]] effects similar to LSD while LSA produces [[sedation]]. LSH is said to produce less vasoconstriction than LSA.

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-It has been documented that '''Lysergic Acid Amide''' (LSA) is capable of forming adducts with various aldehydes. <ref>http://www.nature.com/nature/journal/v192/n4802/abs/192552a0.html</ref> Such adducts can form spontaneously during extraction of LSA if aldehydes are introduced to the solution, and can alter the subjective and physiological effects of LSA. <ref>http://herbpedia.wikidot.com/</ref>
+It has been documented that lysergic acid amide (LSA) is capable of forming adducts with various aldehydes.<ref>http://www.nature.com/nature/journal/v192/n4802/abs/192552a0.html</ref> Such adducts can form spontaneously during the extraction of LSA if aldehydes are introduced to the solution and can alter the subjective and physiological effects of LSA.<ref>http://herbpedia.wikidot.com/</ref>
-==Lysergic Acid Hydroxyethylamide==
+==Lysergic acid hydroxyethylamide==
-'''Lysergic Acid Hydroxyethylamide''' (LSH) is one example of such adducts, produced from LSA and acetaldehyde.
+Lysergic acid hydroxyethylamide (LSH) is one example of such adducts, which is produced from LSA and acetaldehyde.
-Due to the low boiling point of acetaldehyde (20.2 °C), LSH is very unstable and readily decomposes back into LSA and acetaldehyde. LSH and possibly other adducts are formed naturally in LSA containing plants, possibly explaining the differences in reported effects, as fresh seeds may contain higher levels of LSH.
+Due to the low boiling point of acetaldehyde (20.2 °C), LSH is very unstable and readily decomposes back into LSA and acetaldehyde. LSH and possibly other adducts are formed naturally in LSA containing plants, possibly explaining the differences in reported effects as fresh seeds may contain higher levels of LSH.
-LSA is possibly not the main active principal of Ipomea seeds as commonly thought, and appears instead to be a decomposition product of lysergic acid hydroxyethylamide (LSH). LSH is reported to have psychedelic properties similar to that of '''Lysergic Acid Diethylamide''' (LSD). Animal tests have shown that LSH produces stimulant effects similar to LSD, while LSA produces sedation. LSH is said to produce less vasoconstriction than LSA.
+LSA is possibly not the main active principal of Ipomea seeds as commonly thought and appears instead to be a decomposition product of lysergic acid hydroxyethylamide (LSH). LSH is reported to have psychedelic properties similar to that of lysergic acid diethylamide (LSD). Animal tests have shown that LSH produces [[stimulation|stimulant]] effects similar to LSD while LSA produces [[sedation]]. LSH is said to produce less vasoconstriction than LSA.
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