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2C-D: Difference between revisions
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| ''[[2C-D/Summary|Summary sheet: 2C-D]]'' | | ''[[2C-D/Summary|Summary sheet: 2C-D]]'' | ||
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'''2C-D''' ('''2,5-dimethoxy-4-methylphenethylamine''', also known as '''2C-M''') is a [[Chemical class::phenethylamine]] [[Psychoactive class::psychedelic]] drug of the [[2C-x]] family that is sometimes used as an [[entheogen]]. It was first synthesized in 1970 by a team from the Texas Research Institute of Mental Sciences,<ref>https://www.ncbi.nlm.nih.gov/pubmed/5412084</ref> and its activity was subsequently investigated in humans by [[Alexander Shulgin]]<ref>Alexander Shulgin - PIHKAL | http://www.erowid.org/library/books_online/pihkal/pihkal033.shtml</ref>. The full name of the chemical is '''2,5-dimethoxy-4-methylphenethylamine'''. In his book PiHKAL (Phenethylamines i Have Known And Loved), Shulgin lists the dosage range as being from 20 to 60 mg and many people recommend higher doses. Lower doses (generally 10 mg or less) of 2C-D have been explored as a potential nootropic, albeit with mixed results. 2C-D is generally taken orally, though may be insufflated (i.e., taken nasally). Insufflating tends to cause intense pain, however, and the dosage level is usually much lower, typically in the region of 1 to 15 mg. | '''2C-D''' ('''2,5-dimethoxy-4-methylphenethylamine''', also known as '''2C-M''') is a [[Chemical class::phenethylamine]] [[Psychoactive class::psychedelic]] drug of the [[2C-x]] family that is sometimes used as an [[entheogen]]. It was first synthesized in 1970 by a team from the Texas Research Institute of Mental Sciences,<ref>Amphetamine analogs. II. Methylated phenethylamines | https://www.ncbi.nlm.nih.gov/pubmed/5412084</ref> and its activity was subsequently investigated in humans by [[Alexander Shulgin]]<ref>Alexander Shulgin - PIHKAL | http://www.erowid.org/library/books_online/pihkal/pihkal033.shtml</ref>. The full name of the chemical is '''2,5-dimethoxy-4-methylphenethylamine'''. In his book PiHKAL (Phenethylamines i Have Known And Loved), Shulgin lists the dosage range as being from 20 to 60 mg and many people recommend higher doses. Lower doses (generally 10 mg or less) of 2C-D have been explored as a potential nootropic, albeit with mixed results. 2C-D is generally taken orally, though may be insufflated (i.e., taken nasally). Insufflating tends to cause intense pain, however, and the dosage level is usually much lower, typically in the region of 1 to 15 mg. | ||
Not much information is known about the toxicity of 2C-D, as no major studies have been conducted. According to Shulgin, the effects of 2C-D typically last for 4–6 hours. Shulgin himself referred to this substance as a “pharmacological tofu,” meaning that when mixed with other substances, it can extend or potentiate their effects without coloring the experience too much, in a manner similar to how tofu absorbs the flavors of sauces or spices it is cooked with. Some people have claimed 2C-D is relatively uninteresting on its own, but many other users have strongly disagreed with this assessment and believe that 2C-D is a true psychedelic in its own right. | Not much information is known about the toxicity of 2C-D, as no major studies have been conducted. According to Shulgin, the effects of 2C-D typically last for 4–6 hours. Shulgin himself referred to this substance as a “pharmacological tofu,” meaning that when mixed with other substances, it can extend or potentiate their effects without coloring the experience too much, in a manner similar to how tofu absorbs the flavors of sauces or spices it is cooked with. Some people have claimed 2C-D is relatively uninteresting on its own, but many other users have strongly disagreed with this assessment and believe that 2C-D is a true psychedelic in its own right. | ||
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==Chemistry== | ==Chemistry== | ||
[[File:SubstitutedPhenethylamine.png|thumb|right|280px||General formula of phenethylamine molecule.]] | [[File:SubstitutedPhenethylamine.png|thumb|right|280px||General formula of phenethylamine molecule.]] | ||
2C-D or 2,5-dimethoxy-4-methylphenethylamine is a substituted [[phenethylamines|phenethylamine]] featuring a phenyl ring bound to an amino (NH<sub>2</sub>) group through an ethyl chain. 2C-D contains methoxy functional groups CH<sub>3</sub>O- attached to carbons R<sub>2</sub> and R<sub>5</sub> as well as a methyl group attached to carbon R<sub>4</sub> of the phenyl ring. 2C-D belongs to the 2C family of phenethylamines which contain methoxy groups on the 2 and 5 positions of the benzene ring. <ref>http://isomerdesign.com/PiHKAL/read.php?id=22</ref> | 2C-D or 2,5-dimethoxy-4-methylphenethylamine is a substituted [[phenethylamines|phenethylamine]] featuring a phenyl ring bound to an amino (NH<sub>2</sub>) group through an ethyl chain. 2C-D contains methoxy functional groups CH<sub>3</sub>O- attached to carbons R<sub>2</sub> and R<sub>5</sub> as well as a methyl group attached to carbon R<sub>4</sub> of the phenyl ring. 2C-D belongs to the 2C family of phenethylamines which contain methoxy groups on the 2 and 5 positions of the benzene ring. <ref>2,5-Dimethoxy-4-chlorophenethylamine (IsomerDesign / PiHKAL) http://isomerdesign.com/PiHKAL/read.php?id=22</ref> | ||
==Pharmacology== | ==Pharmacology== | ||