Prochlorperazine: Difference between revisions
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==Chemistry== | ==Chemistry== | ||
Prochlorperazine is a piperazine derivative of the phenothiazine class of organic compounds. Prochlorperazine contains a thiazine ring, a six-member ring which includes one nitrogen and one sulfur atom. The thiazine ring is fused to two benzene rings, creating a tricyclic phenothiazine. Prochlorperazine contains a chlorine atom bound to R<sub>2</sub> of the phenothiazine group. Additionally, bound at R<sub>10</sub> to the nitrogen atom of the structure, is a three carbon propyl chain. The propyl chain is bound at it's terminal carbon to a piperazine ring at R<sub>1</sub>. Piperazine is a six-membered saturated ring with two nitrogen atoms at positions 1 and 4. The piperazine ring of prochlorperazine is also substituted at R<sub>4</sub> with a methyl group. Prochlorperazine is found in pills as a maleate. It is analagous to [[chlorpromazine]], another anti-psychotic phenothiazine. | Prochlorperazine is a piperazine derivative of the phenothiazine class of organic compounds. Prochlorperazine contains a thiazine ring, a six-member ring which includes one nitrogen and one sulfur atom. The thiazine ring is fused to two benzene rings, creating a tricyclic phenothiazine. Prochlorperazine contains a chlorine atom bound to R<sub>2</sub> of the phenothiazine group. Additionally, bound at R<sub>10</sub> to the nitrogen atom of the structure, is a three carbon propyl chain. The propyl chain is bound at it's terminal carbon to a piperazine ring at R<sub>1</sub>. Piperazine is a six-membered saturated ring with two nitrogen atoms at positions 1 and 4. The piperazine ring of prochlorperazine is also substituted at R<sub>4</sub> with a methyl group. Prochlorperazine is found in pills as a maleate. It is analagous to [[chlorpromazine]], another anti-psychotic phenothiazine. | ||
==Pharmacology== | ==Pharmacology== |